Human EN-RAGE/S100A12 ELISA Kit/人EN-RAGE / S100A12 ELISA试剂盒
货号：EH170RB,EH170RBX5,EH170RBX10
规格：96 Tests,5X96 Tests,10X96 tests
价格：6641,29884,57271
产品类型：Platinum ELISA
品牌：Thermo Fisher
物种：人
宿主：其它
抗体亚型：其它
荧光染料：其它
灵敏度 | 0.82 ng/mL |
| 检测范围 | 0.82-200 ng/mL |
样本类型/体积 | 血清 50 μL 血浆 50 μL 上清液 50 μL |
操作时间 | 1 hr 20 min |
测试时间 | 4 hr 45 min |
Homogenous (no wash) | No |
| 批间变异系数（CV） | <12% |
| 批内变异系数（CV） | <10% |
仪器设备 | Colorimetric Microplate Reader 酶标仪 |
规格 | 5 x 96 Tests |
组份 | - 预包被96孔板 - 标准品 - 测定稀释浓缩液 - 生物素化检测抗体 - SAV-HRP - 洗涤液 - 显色剂 - 终止液 - 胶板盖 |
储存温度 | 2-8℃ |
| Protein name | S100A12 |
| Protein aliases | CAAF1, CAGC, Calcitermin, Calcium-binding protein in amniotic fluid 1, calgranulin C, Calgranulin-C, CGRP, EN-RAGE, Extracellular newly identified RAGE-binding protein, Migration inhibitory factor-related protein 6, MRP-6, Neutrophil S100 protein, Protein S100-A12, S100 calcium-binding protein A12, S100 calcium-binding protein A12 (calgranulin C) |
物种（Tested） | 人 |
试剂盒类型 | Sandwich ELISA Kit |
标记（染料） | HRP |
| 检测抗体偶联物 | Biotin |
| Gene aliases | CAAF1, CAGC, CGRP, ENRAGE, MRP-6, MRP6, p6, S100A12 |
| Gene ID | (Human) 6283 |
| Gene symbol | S100A12 |
| UniProt ID | (Human) P80511 |
| Human EN-RAGE/S100A12 quantitates human EN-RAGE/S100A12 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human EN-RAGE/S100A12.人EN-RAGE / S100A12定量测定血清，血浆，上清液中的人EN-RAGE / S100A12。 该检测试剂盒将专门识别天然和重组人EN-RAGE / S100A12。Target information 靶标信息S100A12 is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100A12 is proposed to be involved in specific calcium-dependent signal transduction pathways and its regulatory effect on cytoskeletal components may modulate various neutrophil activities. S100A12 is also a ligand for RAGE. Interaction with RAGE on mononuclear phagocytes, lymphocytes and endothelium triggers cellular activation. Nuclear factor kappa B, a key transcription factor for inflammatory events, is activated by S100A12/RAGE. S100A12 has also been shown to have anti-microbial properties.S100A12是包含2个EF手钙结合基序的S100蛋白家族的成员。 S100蛋白位于大量细胞的细胞质和/或细胞核中，并参与许多细胞过程的调控，例如细胞周期进程和分化。 S100A12被提议参与特定的钙依赖性信号转导途径，其对细胞骨架成分的调节作用可能会调节各种中性粒细胞的活性。 S100A12还是RAGE的配体。 与RAGE在单核吞噬细胞，淋巴细胞和内皮细胞上的相互作用触发细胞活化。 S100A12 / RAGE可激活核因子κB（炎症事件的关键转录因子）。 S100A12也已被证明具有抗微生物特性。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。 |
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