Rat IL-23 ELISA Kit/大鼠IL-23 ELISA试剂盒
货号：ERA28RB,ERA28RBX5
规格：96 Tests,5X96 Tests
价格：6327,28472
产品类型：Platinum ELISA
品牌：Thermo Fisher
物种：大鼠
宿主：其它
抗体亚型：其它
荧光染料：其它
灵敏度 | 0.82 ng/mL |
| 检测范围 | 0.82-200 ng/mL |
样本类型/体积 | 血清 50 μL 血浆 50 μL 上清液 50 μL |
操作时间 | 1 hr 20 min |
测试时间 | 4 hr 45 min |
Homogenous (no wash) | No |
| 批间变异系数（CV） | <12% |
| 批内变异系数（CV） | <10% |
仪器设备 | Colorimetric Microplate Reader 酶标仪 |
规格 | 5 x 96 Tests |
组份 | - 预包被96孔板 - 标准品 - 测定稀释浓缩液 - 生物素化检测抗体 - SAV-HRP - 洗涤液 - 显色剂 - 终止液 - 胶板盖 |
储存温度 | 2-8℃ |
| Protein name | IL-23 p19 |
| Protein aliases | IL-23 subunit alpha, IL-23-A, IL-23p19, Interleukin-23 subunit alpha, Interleukin-23 subunit p19 |
物种（Tested） | 大鼠 |
试剂盒类型 | Sandwich ELISA Kit |
标记（染料） | HRP |
| 检测抗体偶联物 | Biotin |
| Gene aliases | Il23a |
| Gene ID | (Rat) 155140 |
| Gene symbol | Il23a |
| UniProt ID | (Rat) Q91Z84 |
| Rat IL-23 quantitates rat IL-23 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant rat IL-23.大鼠IL-23定量测定血清，血浆，上清液中的大鼠IL-23。该检测试剂盒将只识别天然和重组大鼠IL-23。Target information 靶标信息IL-23 is a heterodimeric cytokine composed of the p40 subunit of IL-12 disulfide-linked with a protein p19. p19, like p35 of IL-12, is biologically inactive by itself. IL-23 interacts with IL-12Rbeta1 and an additional, novel beta2-like receptor subunit with STAT4 binding domain, termed IL-23R. IL-23 is secreted by activated mouse and human dendritic cells. Biological activities of mouse IL-23 are distinct from those of mouse IL-12. Mouse IL-23 was found not to induce significant amounts of IFN-γ. Mouse IL-23 does induce strong proliferation of memory T cells (but not naive T cells), whereas IL-12 has no effect on memory cells. Additionally, mouse IL-23 (but not IL-12) can activate mouse memory T cells to produce the proinflammatory cytokine IL-17. Human IL-23 has biological properties which are less distinct from human IL-12; human IL-23 induces proliferation of memory T cells and induces moderate levels of IFN-γ production by naive and memory T cells, as compared to IL-12.IL-23是一种异源二聚体细胞因子，由与蛋白质p19连接的IL-12二硫键的p40亚基组成。与IL-12的p35一样，p19本身也没有生物学活性。 IL-23与IL-12Rbeta1和另一个具有STAT4结合域的新型beta2样受体亚基（称为IL-23R）相互作用。 IL-23由活化的小鼠和人树突状细胞分泌。小鼠IL-23的生物学活性不同于小鼠IL-12的生物学活性。发现小鼠IL-23不会诱导大量的IFN-γ。小鼠IL-23确实会诱导记忆T细胞（而非幼稚T细胞）强烈增殖，而IL-12对记忆细胞没有影响。此外，小鼠IL-23（但不是IL-12）可以激活小鼠记忆T细胞以产生促炎性细胞因子IL-17。人IL-23具有与人IL-12不同的生物学特性；与IL-12相比，人IL-23诱导记忆T细胞增殖并诱导幼稚和记忆T细胞中等水平的IFN-γ产生。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。 |
©
Bio-Rad伯乐代理官网-伯乐抗体-伯乐层析Aminex色谱柱是专业的授权总代理区域代理经销平台。
© 如需询价，请加客服QQ：1749072012 、客服微信：jinshanbio，或发送邮件到1749072012@qq.com
© 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务，数据资源基于CC协议。
© 本文地址：
https://biorod.cn/thread-24870.htm
QQ:1749072012