Rat CD-80 ELISA Kit/大鼠CD-80 ELISA试剂盒
货号：ERA6RB,ERA6RBX5
规格：96 Tests,5X96 Tests
价格：6641,29884
产品类型：Platinum ELISA
品牌：Thermo Fisher
物种：大鼠
宿主：其它
抗体亚型：其它
荧光染料：其它
灵敏度 | 1.23 ng/mL |
| 检测范围 | 1.23-300 ng/mL |
样本类型/体积 | 血清 50 μL 血浆 50 μL 上清液 50 μL |
操作时间 | 1 hr 20 min |
测试时间 | 4 hr 45 min |
Homogenous (no wash) | No |
| 批间变异系数（CV） | <12% |
| 批内变异系数（CV） | <10% |
仪器设备 | Colorimetric Microplate Reader 酶标仪 |
规格 | 5 x 96 Tests |
组份 | - 预包被96孔板 - 标准品 - 测定稀释浓缩液 - 生物素化检测抗体 - SAV-HRP - 洗涤液 - 显色剂 - 终止液 - 胶板盖 |
储存温度 | 2-8℃ |
| Protein name | CD80 (B7-1) |
| Protein aliases | Cd80 a rat homolog of the human CD28/CTLA - 4 ligand (B7-1), CD80 antigen, T-lymphocyte activation antigen CD80 |
物种（Tested） | 大鼠 |
试剂盒类型 | Sandwich ELISA Kit |
标记（染料） | HRP |
| 检测抗体偶联物 | Biotin |
| Gene aliases | B7-1 |
| Gene ID | (Rat) 25408 |
| Gene symbol | Cd80 |
| Rat CD-80 quantitates rat CD-80 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant rat CD-80.大鼠CD-80可定量测定血清，血浆，上清液中的大鼠CD-80。 该检测试剂盒将只识别天然和重组大鼠CD-80。Target information 靶标信息CD80 (B7-1) and CD86 (B7-2) are ligands of T cell critical costimulatory molecule CD28, and of an inhibitory receptor CTLA-4 (CD152). Both B7 molecules are expressed on professional antigen-presenting cells and are essential for T cell activation, and both molecules can also substitute for each other in this process. CD80 is rapidly induced on the surface of in vitro activated B cells, with Epstein Barr Virus (EBV) transformed B cell lines, with Burkitts lymphoma cell lines, with freshly isolated follicular B lymphoma cells, T cells, and monocytes. The B-lymphocyte activation antigen B7-1 provides regulatory signals for T lymphocytes as a consequence of binding to the CD28 and CTLA4 ligands of T cells. Diseases associated with CD80 dysfunction include gallbladder squamous cell carcinoma and myocarditis.CD80（B7-1）和CD86（B7-2）是T细胞关键共刺激分子CD28和抑制受体CTLA-4（CD152）的配体。 两个B7分子均在专业抗原呈递细胞上表达，并且对于T细胞活化至关重要，并且在此过程中，两个分子也可以彼此替代。 CD80可通过爱泼斯坦巴尔病毒（EBV）转化的B细胞系，伯基兹淋巴瘤细胞系，新鲜分离的滤泡性B淋巴瘤细胞，T细胞和单核细胞在体外活化的B细胞表面快速诱导。 由于与T细胞的CD28和CTLA4配体结合，B淋巴细胞活化抗原B7-1为T淋巴细胞提供了调节信号。 与CD80功能障碍有关的疾病包括胆囊鳞状细胞癌和心肌炎。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。 |
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