JARID1A/RBP2 Polyclonal Antibody

货号：IHC-00479 ,IHC-00479-T

规格：100μL,10μL

价格：6448,1886

产品类型：标签抗体

品牌：Thermo Fisher

抗原：Between 1640 and 1690

物种：人

宿主：兔

抗体亚型：IgG

荧光染料：其它

类型:	一抗	同型对照：
浓度：	0.25 mg/mL	用法：	1:100-1:500(IHC)

产品详细信息The recommended shelf life for this product is 1 year from date of receipt.Based on 100% sequence identity, this antibody is predicted to react with Mouse, Rat, Dog, Horse, Rabbit, Guinea pig_10141, Panda, Orangutan, Gorilla and Northern white-cheeked gibbon靶标信息UPF3B is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. The protein is one of two functional homologs to yeast Upf3p. This protein binds to the mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein. It forms with Y14 a complex that binds specifically 20 nt upstream of exon-exon junctionsThis gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. The encoded protein is one of two functional homologs to yeast Upf3p. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein binds to the mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein. It forms with Y14 a complex that binds specifically 20 nt upstream of exon-exon junctions. This gene is located on the long arm of chromosome X. Two splice variants encoding different isoforms have been found for this gene.

数据：

JARID1A/RBP2 Antibody (IHC-00479) in IHCDetection of human JARID1A/RBP2 by immunohistochemistry.Sample:FFPE section of human prostate carcinoma.Antibody:Affinity purified rabbit anti-JARID1A/RBP2 (Cat. No. IHC-00479) used at a dilution of 1:250.Detection:DAB.

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