Bovine IL-1 alpha/IL-1 F1 ELISA Kit/牛IL-1 alpha / IL-1 F1 ELISA试剂盒
货号：EB7RB,EB7RBX5,EB7RBX10
规格：96 Tests,5X96 Tests,10X96 tests
价格：6641,29884,57271
产品类型：Platinum ELISA
品牌：Thermo Fisher
物种：其它
宿主：其它
抗体亚型：其它
荧光染料：其它
灵敏度 | 16 pg/mL |
| 检测范围 | 16.38-4,000 pg/mL |
样本类型/体积 | 血清 50 μL 血浆 50 μL 上清液 50 μL |
操作时间 | 1 hr 20 min |
测试时间 | 4 hr 45 min |
Homogenous (no wash) | No |
| 批间变异系数（CV） | <12% |
| 批内变异系数（CV） | <10% |
仪器设备 | Colorimetric Microplate Reader 酶标仪 |
规格 | 5 x 96 Tests |
组份 | - 预包被96孔板 - 标准品 - 测定稀释浓缩液 - 生物素化检测抗体 - SAV-HRP - 洗涤液 - 显色剂 - 终止液 - 胶板盖 |
储存温度 | 2-8℃ |
| Protein name | IL-1 alpha |
| Protein aliases | IL-1 alpha, Interleukin-1 alpha, interleukin-1 alpha precursor |
物种（Tested） | 牛 |
试剂盒类型 | Sandwich ELISA Kit |
标记（染料） | HRP |
| 检测抗体偶联物 | Biotin |
| Gene aliases | IL1A |
| Gene ID | (Bovine) 281250 |
| Gene symbol | IL1A |
| Bovine IL-1 alpha/IL-1 F1 quantitates bovine IL-1 alpha/IL-1 F1 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant bovine IL-1 alpha/IL-1 F1.牛IL-1 alpha / IL-1 F1定量测定血清，血浆，上清液中的牛IL-1 alpha / IL-1 F1。该检测试剂盒将专门识别天然和重组牛IL-1α/ IL-1 F1。Target information 靶标信息IL-1 alpha (Interleukin-1 alpha) is a proinflammatory cytokine expressed by monocytes, macrophages, and dendritic cells. IL-1 alpha is coded by the IL1A gene and signals through two receptors, IL-1RI and IL-1RII, both of which are shared with IL-1 beta. IL1A is located on the q arm on chromosome 2 at position 13. IL-1 alpha plays an important role in innate host defense by triggering the production of other proinflammatory cytokines in target cells and initiating acute-phase responses. IL-1 alpha activity can be moderated by IL-1 Receptor Antagonist (IL-1RA), a protein produced by many cell types that blocks receptor binding through competitive inhibition. IL-1 alpha is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. Further, IL-1 alpha is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury and induces apoptosis. The IL1A gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. IL1 alpha regulates the activities of NF-kappaB and mitogen-activated protein kinases. IL-1 alpha can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of IL-1 alpha are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.IL-1 alpha（白介素-1 alpha）是单核细胞，巨噬细胞和树突状细胞表达的促炎细胞因子。 IL-1 alpha由IL1A基因编码，并通过两个受体IL-1RI和IL-1RII发出信号，这两个受体均与IL-1 beta共享。 IL1A位于2号染色体第13位的q臂上。IL-1alpha通过触发靶细胞中其他促炎细胞因子的产生并启动急性期反应，在先天宿主防御中发挥重要作用。 IL-1受体拮抗剂（IL-1RA）可以调节IL-1α的活性，IL-1RA是许多细胞类型产生的蛋白质，通过竞争性抑制作用阻断受体结合。 IL-1α是参与多种免疫反应，炎症过程和造血作用的多效细胞因子。此外，IL-1α由单核细胞和巨噬细胞产生为前蛋白，其被蛋白水解处理并响应细胞损伤而释放并诱导凋亡。 IL1A基因和其他8个白介素1家族基因在2号染色体上形成一个细胞因子基因簇。IL1α调节NF-κB和有丝分裂原激活的蛋白激酶的活性。 IL-1α可以刺激IL6和环氧合酶2（PTGS2 / COX-2）的表达，并增强一氧化氮（NO）的产生。高水平的IL-1α与几种慢性炎症性疾病有关，包括类风湿关节炎，牛皮癣和多发性硬化症。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。 |
©
Bio-Rad伯乐代理官网-伯乐抗体-伯乐层析Aminex色谱柱是专业的授权总代理区域代理经销平台。
© 如需询价，请加客服QQ：1749072012 、客服微信：jinshanbio，或发送邮件到1749072012@qq.com
© 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务，数据资源基于CC协议。
© 本文地址：
https://biorod.cn/thread-25007.htm
QQ:1749072012