L3MBTL1 Polyclonal Antibody

货号：PA5-30499

规格：100 µL

价格：4880

产品类型：标签抗体

品牌：Thermo Fisher

抗原：Recombinant fragment corresponding to a region wit

物种：人

宿主：兔

抗体亚型：IgG

荧光染料：其它

类型:	一抗	同型对照：
浓度：	1 mg/mL	用法：	1:100-1:1000(ICC);1:100-1:1000(IF);1:500-1:3,000(WB)

产品详细信息Recommended positive controls: HeLa nucleus, human L3MBTL-transfected 293T.Predicted reactivity: Mouse (83%).Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.靶标信息L3MBTL1 is the homolog of a protein identified in Drosophila as a suppressor of malignant transformation of neuroblasts and ganglion-mother cells in the optic centers of the brain. L3MBTL1 is localized to condensed chromosomes in mitotic cells and overexpression of this protein in a glioma cell line results in improper nuclear segregation and cytokinesis producing multinucleated cells. L3MBTL1 represents a polycomb group gene the encoded protein functions to regulate gene activity, likely via chromatin modification. Polycomb group protein specifically recognizes and binds mono- and dimethyllysine residues on target proteins, thereby acting as a reader of a network of post-translational modifications. Alternatively spliced transcript variants encoding different isoforms of the L3MBTL1 gene have been identified.

数据：

L3MBTL1 Antibody (PA5-30499) in IFImmunofluorescent analysis of L3MBTL in paraformaldehyde-fixed HeLa cells using a L3MBTL polyclonal antibody (Product # PA5-30499) (Green) at a 1:500 dilution. Alpha-tubulin filaments were labeled withProduct # PA5-29281(Red) at a 1:2000. L3MBTL1 Antibody (PA5-30499) in WBWestern blot analysis of L3MBTL using A) 30 µg 293T whole cell lysate and B) 30 µg whole cell lysate of human L3MBTL-transfected 293T cells. Samples were loaded onto a 7.5% SDS-PAGE gel and probed with a L3MBTL polyclonal antibody (Product # PA5-30499) at a dilution of 1:5000.

推荐产品：

二抗荧光二抗免疫组化一抗标签抗体

技术参数

© Bio-Rad伯乐代理官网-伯乐抗体-伯乐层析Aminex色谱柱是专业的授权总代理区域代理经销平台。
© 如需询价，请加客服QQ：1749072012 、客服微信：jinshanbio，或发送邮件到1749072012@qq.com
© 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务，数据资源基于CC协议。
© 本文地址：https://biorod.cn/thread-25048.htm