Mouse ALK-1 ELISA Kit/小鼠ALK-1 ELISA试剂盒
货号:EM6RB,EM6RBX5,EM6RBX10
规格:96 Tests,5X96 Tests,10X96 tests
价格:6327,28472,54564
产品类型:Platinum ELISA
品牌:Thermo Fisher
物种:小鼠
宿主:其它
抗体亚型:其它
荧光染料:其它
灵敏度 | 0.41 ng/mL |
检测范围 | 0.41-100 ng/mL |
样本类型/体积 | 血清 50 μL 血浆 50 μL 上清液 50 μL |
操作时间 | 1 hr 20 min |
测试时间 | 4 hr 45 min |
Homogenous (no wash) | No |
批间变异系数(CV) | <12% |
批内变异系数(CV) | <10% |
仪器设备 | Colorimetric Microplate Reader 酶标仪 |
规格 | 5 x 96 Tests |
组份 | - 预包被96孔板 - 标准品 - 测定稀释浓缩液 - 生物素化检测抗体 - SAV-HRP - 洗涤液 - 显色剂 - 终止液 - 胶板盖 |
储存温度 | 2-8℃ |
Protein name | ACVRL1 |
Protein aliases | Activin receptor-like kinase 1, activin receptor-like kinase-1, ALK-1, Serine/threonine-protein kinase receptor R3, SKR3, TGF-B superfamily receptor type I, TSR-I |
物种(Tested) | 小鼠 |
试剂盒类型 | Sandwich ELISA Kit |
标记(染料) | HRP |
检测抗体偶联物 | Biotin |
Gene aliases | Acvrl1, Acvrlk1, AI115505, AI427544, Alk-1, Alk1 |
Gene ID | (Mouse) 11482 |
Gene symbol | Acvrl1 |
UniProt ID | (Mouse) Q61288 |
Mouse ALK-1 quantitates mouse ALK-1 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant mouse ALK-1.小鼠ALK-1定量分析血清,血浆,上清液中的小鼠ALK-1。 该检测试剂盒将专门识别天然和重组小鼠ALK-1。Target information 靶标信息The TGF-beta superfamily of ligands exerts its biological activity by binding to heteromeric receptor complexes two types (I and II) of the serine/threonine kinases. ALK1, like the other type I receptors, contains a cysteine rich domain with conserved cysteine spacing in the extracellular region and a glycine and serine rich domain preceding the kinase domain. The reduced human ALK1 monomer has a calculated molecular mass of approximately 37.3 kDa. Due to glycoslyation, the recombinant human protein migrates as a 50-55 kDa protein in SDS-PAGE under reducing conditions. Human and mouse ALK1 share approximately 71% amino acid sequence identity in their extracellular domains. ALK1 is highly expressed in endothelial cells and other vascular tissues.TGF-β配体超家族通过与丝氨酸/苏氨酸激酶的两种(I和II)异源受体复合物结合而发挥其生物学活性。 像其他I型受体一样,ALK1包含一个富含半胱氨酸的结构域,在胞外区域具有保守的半胱氨酸间隔,以及一个位于激酶结构域之前的富含甘氨酸和丝氨酸的结构域。 还原的人ALK1单体的计算分子量约为37.3kDa。 由于糖基化作用,重组人蛋白质在还原条件下以50-55 kDa的蛋白质在SDS-PAGE中迁移。 人和小鼠ALK1在其细胞外结构域中共享大约71%的氨基酸序列同一性。 ALK1在内皮细胞和其他血管组织中高表达。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。 |
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