BRD4 Polyclonal Antibody

货号：PA5-82519

规格：100 µL

价格：6049

产品类型：标签抗体

品牌：Thermo Fisher

抗原：Recombinant protein corresponding to Human BRD4

物种：人

宿主：兔

抗体亚型：IgG

荧光染料：其它

类型:	一抗	同型对照：
浓度：	0.2mg/mL	用法：	0.25-2 µg/mL（ICC）；0.25-2 µg/mL(IF);1:500-1:1,000(IHC(P)）

产品详细信息Immunogen sequence: PQPAKPQQVI QHHHSPRHHK SDPYSTGHLR EAPSPLMIHS PQMSQFQSLT HQSPPQQNVQ PKKQELRAAS VVQPQPLVVV KEEKIHSPII RSEPFSPSLR PEPPKHPESI KAPVHLPQRP EMKPVDVGRP VIRPPEQNAP PP靶标信息BRD4, a ubiquitously expressed nuclear phosphoprotein, is a member of BET protein family. It is a human homolog of mouse MCAP and consists of 2 N-terminal bromodomains, a central ET-domain, and several kinase-like motifs in its N-terminus. It is expressed as 2 isoforms; the longer variant has a C-terminus region with a praline and glutamine-rich domains. BRD4 is a chromatin-binding protein whose expression is induced in response to growth stimuli. BRD4 acts at different stages of the cell cycleby interacting with proteins including RFC and SPA-1 and regulates cell growth. It also has a role in regulating chromosomal dynamics during mitosis. BRD4 functions as a cellular target for E2 protein of papillomavirus.

数据：

BRD4 Antibody (PA5-82519) in IFImmunofluorescent analysis of BRD4 in U-251 MG cells using a BRD4 polyclonal antibody (Product # PA5-82519). The analysis shows localization to nucleoplasm. BRD4 Antibody (PA5-82519) in IHCImmunohistochemical analysis of BRD4 in human placenta using a BRD4 polyclonal antibody (Product # PA5-82519). The analysis shows high expression

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