Rabbit IL-17A ELISA Kit/兔THE 17A ELISA试剂盒
货号：ER6RB,ER6RBX5
规格：96 Tests,5X96 Tests
价格：6641,29884
产品类型：Platinum ELISA
品牌：Thermo Fisher
物种：兔
宿主：其它
抗体亚型：其它
荧光染料：其它
灵敏度 | 0.2 ng/mL |
| 检测范围 | 0.2-50 ng/mL |
样本类型/体积 | 血清 50 μL 血浆 50 μL 上清液 50 μL |
操作时间 | 1 hr 20 min |
测试时间 | 4 hr 45 min |
Homogenous (no wash) | No |
| 批间变异系数（CV） | <12% |
| 批内变异系数（CV） | <10% |
仪器设备 | Colorimetric Microplate Reader 酶标仪 |
规格 | 5 x 96 Tests |
组份 | - 预包被96孔板 - 标准品 - 测定稀释浓缩液 - 生物素化检测抗体 - SAV-HRP - 洗涤液 - 显色剂 - 终止液 - 胶板盖 |
储存温度 | 2-8℃ |
| Protein name | IL-17A |
| Protein aliases | interleukin 17A-like |
物种（Tested） | 兔 |
试剂盒类型 | Sandwich ELISA Kit |
标记（染料） | HRP |
| 检测抗体偶联物 | Biotin |
| Gene ID | (Rabbit) 100339322 |
| Gene symbol | LOC100339322 |
| Rabbit IL-17A quantitates rabbit IL-17A in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant rabbit IL-17A.兔IL-17A定量测定血清，血浆，上清液中的兔IL-17A。该检测试剂盒将只识别天然和重组兔IL-17A。Target information 靶标信息Interleukin-17A (IL-17A, CTLA-8) is a CD4+ T cell-derived cytokine that promotes inflammatory responses in cell lines and is elevated in rheumatoid arthritis, asthma, multiple sclerosis, psoriasis, and transplant rejection. IL-17A is a 32 kDa long, disulfide-linked homodimer consisting of 136 amino acids that is a member of a six-species family of proteins (IL-17A-17F) and signals through the IL-17 receptor (IL-17R/CDw217). High levels of IL-17A homodimer are produced by activated peripheral blood CD4+ T-cells, and IL-17A also enhances expression of the intracellular adhesion molecule-1 (ICAM-1) in human fibroblasts. In particular, human IL-17A also stimulates epithelial, endothelial, or fibroblastic cells to secrete IL-6, IL-8, G-CSF, and PGE2. In the presence of human IL-17A, fibroblasts can sustain the proliferation of CD34+ hematopoietic progenitors and induce maturation into neutrophils. Mouse, rat, and human IL-17A can induce IL-6 secretion in mouse stromal cells, indicating that all homologs can recognize the mouse receptor. IL-17A regulates the activities of NF-kappa B and mitogen-activated protein kinases, stimulates the expression of IL-6 and cyclooxygenase-2 (PTGS2/COX-2), and enhances the production of nitric oxide (NO).白介素-17A（IL-17A，CTLA-8）是CD4 + T细胞衍生的细胞因子，可促进细胞系中的炎症反应，并在类风湿性关节炎，哮喘，多发性硬化症，牛皮癣和移植排斥反应中升高。 IL-17A是一个32 kDa长的，二硫键连接的同型二聚体，由136个氨基酸组成，是六种蛋白质家族（IL-17A-17F）的成员，并通过IL-17受体（IL-17R / CDw217）。活化的外周血CD4 + T细胞产生高水平的IL-17A同型二聚体，并且IL-17A还增强人成纤维细胞中细胞内粘附分子1（ICAM-1）的表达。特别地，人IL-17A还刺激上皮，内皮或成纤维细胞分泌IL-6，IL-8，G-CSF和PGE2。在人IL-17A存在的情况下，成纤维细胞可以维持CD34 +造血祖细胞的增殖并诱导成熟为嗜中性粒细胞。小鼠，大鼠和人IL-17A可以诱导小鼠基质细胞分泌IL-6，这表明所有同源物都可以识别小鼠受体。 IL-17A调节NF-κB和丝裂原激活的蛋白激酶的活性，刺激IL-6和环氧合酶2（PTGS2 / COX-2）的表达，并增强一氧化氮（NO）的产生。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。 |
©
Bio-Rad伯乐代理官网-伯乐抗体-伯乐层析Aminex色谱柱是专业的授权总代理区域代理经销平台。
© 如需询价，请加客服QQ：1749072012 、客服微信：jinshanbio，或发送邮件到1749072012@qq.com
© 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务，数据资源基于CC协议。
© 本文地址：
https://biorod.cn/thread-25152.htm
QQ:1749072012