Ovine IL-6 ELISA Kit/绵羊IL-6 ELISA试剂盒
货号：ESH5RB,ESH5RBX5
规格：96 Tests,5X96 Tests
价格：6641,29884
产品类型：Platinum ELISA
品牌：Thermo Fisher
物种：山羊
宿主：其它
抗体亚型：其它
荧光染料：其它
灵敏度 | 0.15 pg/mL |
| 检测范围 | 0.15-25 pg/mL |
样本类型/体积 | 血清 50 μL 血浆 50 μL 上清液 50 μL |
操作时间 | 1 hr 20 min |
测试时间 | 4 hr 45 min |
Homogenous (no wash) | No |
| 批间变异系数（CV） | <12% |
| 批内变异系数（CV） | <10% |
仪器设备 | Colorimetric Microplate Reader 酶标仪 |
规格 | 5 x 96 Tests |
组份 | - 预包被96孔板 - 标准品 - 测定稀释浓缩液 - 生物素化检测抗体 - SAV-HRP - 洗涤液 - 显色剂 - 终止液 - 胶板盖 |
储存温度 | 2-8℃ |
| Protein name | IL-6 |
| Protein aliases | IL-6, interleukin 6 (interferon, beta 2), Interleukin-6 |
物种（Tested） | 羊 |
试剂盒类型 | Sandwich ELISA Kit |
标记（染料） | HRP |
| 检测抗体偶联物 | Biotin |
| Gene aliases | IL6 |
| Gene ID | (Sheep) 443406 |
| Gene symbol | IL6 |
| UniProt ID | (Sheep) P29455 |
| Ovine IL-6 quantitates ovine IL-6 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant ovine IL-6.绵羊IL-6定量测定血清，血浆，上清液中的绵羊IL-6。该检测试剂盒将只识别天然和重组绵羊IL-6。Target information 靶标信息Interleukin 6 (IL-6) is a multifunctional 26 kD protein originally discovered in the medium of RNA-stimulated fibroblastoid cells. IL-6 appears to be directly involved in the responses that occur after infection and cellular injury, and it may prove to be important as IL-1 and TNF-a in regulating the acute phase response. IL-6 is reported to be produced by fibroblasts, activated T cells, activated monocytes or macrophages and endothelial cells. IL-6 acts upon a variety of cells including myeloid progenitor cells, T cells, B cells, and hepatocytes. In addition, IL-6 appears to interact with IL-2 in the proliferation of T lymphocytes. IL-6 potentiates the proliferative effect of IL-3 on multipotential hematopoietic progenitors. IL-6 plays a critical role in B-cell differentiation to plasma cells and is a potent growth factor for plasmacytoma and myeloma. IL-6 is a very useful culture supplement for the generation of a high number of antibody-producing hybridomas. Primarily produced at sites of acute and chronic inflammation, IL-6 is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of IL-6 is implicated in a wide variety of inflammation-associated disease states including diabetes mellitus and systemic juvenile rheumatoid arthritis.白介素6（IL-6）是一种多功能的26 kD蛋白，最初是在RNA刺激的成纤维细胞样细胞的培养基中发现的。 IL-6直接参与感染和细胞损伤后发生的反应，它可能被证明在调节急性期反应中作为IL-1和TNF-a很重要。据报道IL-6由成纤维细胞，活化的T细胞，活化的单核细胞或巨噬细胞和内皮细胞产生。 IL-6作用于多种细胞，包括骨髓祖细胞，T细胞，B细胞和肝细胞。另外，IL-6在T淋巴细胞的增殖中与IL-2相互作用。 IL-6增强了IL-3对多能造血祖细胞的增殖作用。 IL-6在B细胞向浆细胞的分化中起关键作用，并且是浆细胞瘤和骨髓瘤的有效生长因子。 IL-6是一种非常有用的培养补充剂，可用于产生大量产生抗体的杂交瘤。 IL-6主要在急性和慢性炎症部位产生，分泌到血清中并通过白介素6受体α诱导转录炎症反应。 IL-6的功能涉及多种与炎症相关的疾病状态，包括糖尿病和全身性青少年类风湿性关节炎。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。 |
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