FeraSpin R/肝脏核磁共振成像（MRI ）MRI 造影剂
货号：130-095-138 ,130-095-139
规格：for 5 injections,for 5×5 injections
价格：5348,25403
产品类型：小动物造影剂
品牌：Miltenyi
| FeraSpin R is a nanoparticulate superparamagnetic iron oxide contrast agent specifically formulated for pre-clinical magnetic resonance imaging (MRI).It is a contrast agent of high relaxivity enhancing the contrast in T2- and T2*-weighted MRI due to a shortening of the spin-spin relaxation time (T2).Upon intravenous injection, FeraSpin R is rapidly taken up by the Kupffer cells (macrophages of the liver) resulting in a short blood half-life of a few minutes. FeraSpin R accumulates particularly in the liver and spleen and is degraded with its iron being transferred into the physiological iron stores.FeraSpin R是一种超顺磁化氧化铁纳米微粒造影剂，专门用于临床前磁共振成像(MRI)。其平均颗粒大小较大，粒径分布较广泛，因此易被肝脏及脾脏中的巨噬细胞所摄入。它是一种高松弛度的造影剂，由于缩短了spin-spin relaxation time (T2)时间，增强了T2-和T2*-weightedMRI的对比度。静脉注射后，FeraSinR被Kupffer细胞（肝脏的巨噬细胞）迅速吸收，导致血液半衰期短几分钟。 Fera SpinR在肝脏和脾脏中积累，并随着其铁被转移到生理铁库中而降解。 |
优点： |
| -涵盖全面，应用范围广；- 操作简单； - 高效。 |
数据： |
图1.FeraSpin R 纳米磁珠的结构公式 |
组成成分： |
| ▪850 µL FeraSpin™ R, MRI contrast agent (superparamagnetic iron oxide [SPIO] nanoparticles) or 5×850 µL FeraSpin™ R, MRI contrast agent (superparamagnetic iron oxide [SPIO] nanoparticles). |
相关产品： |
| ▪ExiTron V二聚化非离子胞外CT造影剂（货号#130-095-283）▪ExiTron P CT 肾排泄血管造影剂（货号#130-095-144）▪ExiTron nano 6000 肝脏显像CT 造影剂（货号#130-095-146）▪ExiTron nano 12000CT 血管造影剂（货号#130-095-698）▪GadoSpin F动脉粥样硬化成像剂MRI 造影剂（货号#130-095-162）▪GadoSpin P MR 血管造影剂（货号#130-095-136）▪GadoSpin D动态造影增强MRI 造影剂（货号#130-095-164）▪GadoSpin M 胞外MRI 造影剂（货号#130-095-134）▪FeraSpin R 肝脏显像MRI 造影剂（货号#130-095-138）▪FeraSpin XS 纳米微粒血管MRI 造影剂（货号#130-095-140）▪FeraSpin S 纳米微粒（货号#130-095-166）▪FeraSpin M纳米微粒血管MRI 造影剂（货号#130-095-168）▪FeraSpinL纳米微粒血管MRI 造影剂（货号#130-095-170）▪PolySon H超声微泡（货号#130-095-152）▪PolySon L hard-shell 超声微泡（货号#130-095-150）▪NiraWave C 光学显像造影剂（货号#130-095-154）▪NiraWave M 光学炎症显像造影剂（货号#130-095-157）▪NiraWave nano 780 光学血管造影剂（货号#130-095-693） |
| 参考文献 |
| 1. Lawaczeck, R. et al. (1997) Magnetic iron oxide particles coated with carboxydextran for parenteral administration and liver contrasting. Pre-clinical profile of SH U555A. Acta Radiol. 38: 584-5972. Murakami, T. et al. (2001) Evaluation of regional liver damage by magnetic resonance imaging with superparamagnetic iron oxide in rat liver. Dig. Dis. Sci. 46: 148-155 |
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