CD64 Monoclonal Antibody (10.1), Functional Grade, eBioscience™/CD64 单克隆 (10.1), 功能抗体, eBioscience™

2024-10-18

CD64 Monoclonal Antibody (10.1), Functional Grade, eBioscience™/CD64 单克隆 (10.1), 功能抗体, eBioscience™

货号:16-0649-81,16-0649-85,16-0649-38,16-0649-025,16-0649-050

规格:50 µg,500 µg,5 mg,25 mg,50 mg

价格:1283,3854,24089,72266,120443

产品类型:流式抗体

品牌:eBioscience

抗原:CD64

物种:人

宿主:小鼠

抗体亚型:IgG1, kappa

克隆号:10.1

荧光染料:其它

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类型:

一抗(功能抗体)

同型对照:

Mouse IgG1 kappa Isotype Control (P3.6.2.8.1), Functional Grade, eBioscience™

浓度:

1 mg/mL

用法:

0.5 µg/test(Flow);Assay-Dependent(对照);Assay-Dependent(功能检测)

产品详细信息Description: The 10.1 monoclonal antibody reacts with human CD64 (FcRI), a 75 kDa type I transmembrane protein. CD64 is the high affinity receptor for IgG and is involved in antibody-dependent cell-mediated cytotoxicity (ADCC), phagocytosis, and regulation of cytokine production. Monocytes and macrophages express CD64, while mature granulocytes and lymphocytes are negative.Applications Reported: This 10.1 antibody has been reported for use in flow cytometric analysis, and immunohistology staining of frozen tissue sections.Applications Tested: This 10.1 antibody has been tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at less than or equal to 0.5 µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Storage and handling: Use in a sterile environment.Filtration: 0.2 µm post-manufacturing filtered.Purity: Greater than 90%, as determined by SDS-PAGE.Endotoxin Level: Less than 0.001 ng/µg antibody, as determined by LAL assay.Aggregation: Less than 10%, as determined by HPLC.靶标信息CD64 (FCGR1A) encodes a protein that plays an important role in the immune response. CD64 is a high-affinity Fc-gamma receptor and is one of three related gene family members located on chromosome 1. CD64 plays an important role in the immune response and its dysfunction has been studied in cervical adenitis and tetrasomy 21.仅用于科研。不用于诊断过程。

数据

CD64 Antibody (16-0649-81)mAbs 2015 -Published figure using CD64 monoclonal antibody (Product # 16-0649-81).

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参考文献:

流式1.mAbsRecombinant H22(scFv) blocks CD64 and prevents the capture of anti-TNF monoclonal antibody. A potential strategy to enhance anti-TNF therapy."16-0649 was used in Flow cytometry/Cell sorting to demonstrate the specific blocking of CD64 by H22(scFv) could be used as a mechanism for potentiating the effect of anti-TNF antibodies."功能检测2.Journal of immunology (Baltimore, Md. : 1950)Factor H-IgG Chimeric Proteins as a Therapeutic Approach against the Gram-Positive Bacterial PathogenStreptococcus pyogenes."16-0649 was used in Functional assays to analyse the efficiency of factor H6-7/Fc, a novel antibacterial immunotherapeutic protein, against the Gram-positive bacterium Streptococcus pyogenes."AuthorsBlom AM,Magda M,Kohl L,Shaughnessy J,Lambris JD,Ram S,Ermert D

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