CD162 (PSGL-1) Monoclonal Antibody (4RA10), Functional Grade, eBioscience™/CD162 (PSGL-1) 单克隆 (4RA10), 功能抗体, eBioscience™

货号：16-1621-85

规格：500 µg

价格：4952

产品类型：流式抗体

品牌：eBioscience

抗原：CD162 (PSGL-1)

物种：小鼠

宿主：大鼠

抗体亚型：IgG1, kappa

克隆号：4RA10

荧光染料：其它

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类型:	一抗(功能抗体）	同型对照：	Rat IgG1 kappa Isotype Control (eBRG1), eBioscience™
浓度：	1 mg/mL	用法：	0.25 µg/test（Flow）

产品详细信息Description: This 4RA10 monoclonal antibody reacts with mouse CD162, which is also known as P-selectin glycoprotein ligand-1 (PSGL-1). This clone has been successfully used in flow cytometry and has been reported to block binding of CD162 to CD62P and CD62L.Applications Reported: This 4RA10 antibody has been reported for use in flow cytometric analysis. (Fluorochrome-conjugated 4RA10 is recommended for use in flow cytometry).Applications Tested: This 4RA10 antibody has been tested by flow cytometric analysis of mouse splenocytes. This may be used at less than or equal to 0.25 µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.靶标信息CD162 (PSGL-1) is a 120 kDa homodimer protein found on the surface of leukocytes and platelets. CD162 is known to bind CD62P (P-selectin), CD62L (L-selectin), and to a lower degree CD62E (E-selectin). These interactions play a critical role in leukocyte adhesion, rolling and extravasation. CD162 has been shown to be an important immune marker of T cell exhaustion in chronic viral infections and cancer.仅用于科研。不用于诊断过程。

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