Rabbit anti Human CDK4 antibody
货号：VPA00749
规格：100 µL
价格：3171
产品类型：免疫组化一抗
品牌：Bio-Rad
抗原：CDK4
物种：人
宿主：兔
抗体亚型：IgG
荧光染料：Purified
| 产品介绍 | | |
| Rabbit anti Human CDK4 antibodyrecognizes cyclin-dependent kinase 4, also known as cell division protein kinase 4.The protein encoded by CDK4 is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products ofS. cerevisiaecdc28 andS. pombecdc2. It is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression. The activity of this kinase is restricted to the G1-S phase, which is controlled by the regulatory subunits D-type cyclins and CDK inhibitor p16(INK4a). This kinase was shown to be responsible for the phosphorylation of retinoblastoma gene product (Rb). Mutations in CDK4 as well as in its related proteins including D-type cyclins, p16(INK4a) and Rb were all found to be associated with tumorigenesis of a variety of cancers. Multiple polyadenylation sites of CDK4 have been reported (provided by RefSeq, Jul 2008).Rabbit anti Human CDK4 antibody detects a band of 30 kDa. The antibody has been extensively validated for western blotting using whole cell lysates. |
| 产品详情 | | |
| Target Species | Human |
| Product Form | Purified IgG - liquid |
| Preparation | Rabbit polyclonal antibody purified by affinity chromatography on immunogen. |
| Buffer Solution | Phosphate buffered saline. |
| Preservative Stabilisers | 0.09% Sodium Azide (NaN3)2% Sucrose |
| Immunogen | Synthetic peptide encompassing the center region of human CDK4 |
| Approx. Protein Concentrations | IgG concentration 0.5 mg/ml. |
| Acknowledgements | PrecisionAb is a trademark of Bio-Rad Laboratories. |
| Regulatory | For research purposes only |
| Guarantee | 12 months from date of despatch |
| 存储条件 | | |
| Store undiluted at -20°C, avoiding repeated freeze thaw cycles |
| 应用 | | |
| Application Name | Verified | Min Dilution | Max Dilution |
| Western Blotting | √ | | |
| This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls. |
| 推荐产品 |
| Description | Product Code | Applications | Pack Size |
| Goat anti Rabbit IgG (H/L):HRP | STAR208P | WB | 2 ml |
技术参数 产品应用 WB
产品类型 PrecisionAb Polyclonal
推荐用于 WB
©
Bio-Rad伯乐代理官网-伯乐抗体-伯乐层析Aminex色谱柱是专业的授权总代理区域代理经销平台。
© 如需询价，请加客服QQ：1749072012 、客服微信：jinshanbio，或发送邮件到1749072012@qq.com
© 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务，数据资源基于CC协议。
© 本文地址：
https://biorod.cn/thread-28208.htm
QQ:1749072012