Rabbit anti Human FKBP1A antibody
货号:VPA00601
规格:100 µL
价格:2890
产品类型:免疫组化一抗
品牌:Bio-Rad
抗原:FKBP1A
物种:人
宿主:兔
抗体亚型:IgG
荧光染料:Purified
产品介绍 | | |
Rabbit anti Human FKBP1A antibodyrecognizes the peptidyl-prolyl cis-trans isomerase FKBP1A, also known as 12 kDa FK506-binding protein, 12 kDa FKBP, FKBP12-Exip3, PPIase FKBP1A, calstabin 1, immunophilin FKBP12, protein kinase C inhibitor 2 or rotamase.The protein encoded by the FKBP1A gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium. Multiple alternatively spliced variants, encoding the same protein, have been identified. The human genome contains five pseudogenes related to FKBP1A, at least one of which is transcribed (provided by RefSeq, Sep 2008).Rabbit anti Human FKBP1A gene antibody detects a band of 16 kDa. The antibody has been extensively validated for western blotting using whole cell lysates. |
产品详情 | | |
Target Species | Human |
Product Form | Purified IgG - liquid |
Preparation | Rabbit polyclonal antibody purified by affinity chromatography. |
Buffer Solution | Phosphate buffered saline. |
Preservative Stabilisers | 0.09% Sodium Azide2% Sucrose |
Immunogen | Synthetic peptide directed towards the middle region of human FKBP1A |
Acknowledgements | PrecisionAb is a trademark of Bio-Rad Laboratories. |
Regulatory | For research purposes only |
Guarantee | 12 months from date of despatch |
存储条件 | | |
Store undiluted at -20°C, avoiding repeated freeze thaw cycles |
应用 | | |
Application Name | Verified | Min Dilution | Max Dilution |
Western Blotting | √ | | |
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls. |
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技术参数 产品应用 WB
产品类型 PrecisionAb Polyclonal
推荐用于 WB
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