Rabbit anti Human MEK 2 antibody
货号：VPA00587
规格：100 µL
价格：2890
产品类型：免疫组化一抗
品牌：Bio-Rad
抗原：MEK 2
物种：人
宿主：兔
抗体亚型：IgG
荧光染料：Purified
| 产品介绍 | | |
| Rabbit anti Human MEK 2 antibodyrecognizes MEK 2 also known as dual specificity mitogen-activated protein kinase kinase 2, also known as ERK activator kinase 2, MAP kinase kinase 2, MAPK/ERK kinase 2, MAPKK2 or p45.The protein encoded by MAP2K2 gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. Mutations in MAP2K2 gene cause Cardiofaciocutaneous syndrome 4 (CFC4), a disease characterized by heart defects, mental retardation, and distinctive facial features similar to those found inNoonan syndrome(Schulzet al.2008). The inhibition or degradation of this kinase is also found to be involved in the pathogenesis ofYersiniaand anthrax. A pseudogene, which is located on chromosome 7, has been identified for MAP2K2 (provided by RefSeq, Jul 2008).Rabbit anti Human MEK 2 antibody detects a band of 49 kDa. The antibody has been extensively validated for western blotting using whole cell lysates. |
| 产品详情 | | |
| Target Species | Human |
| Product Form | Purified IgG - liquid |
| Preparation | Rabbit polyclonal antibody purified by affinity chromatography. |
| Buffer Solution | Phosphate buffered saline. |
| Preservative Stabilisers | 0.09% Sodium Azide2% Sucrose |
| Immunogen | Synthetic peptide directed towards the N terminal region of human MEK 2 |
| Acknowledgements | PrecisionAb is a trademark of Bio-Rad Laboratories. |
| Regulatory | For research purposes only |
| Guarantee | 12 months from date of despatch |
| 存储条件 | | |
| Store undiluted at -20°C, avoiding repeated freeze thaw cycles |
| 应用 | | |
| Application Name | Verified | Min Dilution | Max Dilution |
| Western Blotting | √ | | |
| This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls. |
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技术参数 产品应用 WB
产品类型 PrecisionAb Polyclonal
推荐用于 WB
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