CD96 (TACTILE) Monoclonal Antibody (6A6), Functional Grade, eBioscience™/CD96 (TACTILE) 单克隆 (6A6), 功能抗体, eBioscience™
货号：16-0960-82,16-0960-38
规格：100 µg,5 mg
价格：2103,24089
产品类型：流式抗体
品牌：eBioscience
抗原：CD96
物种：小鼠
宿主：大鼠
抗体亚型：其它
克隆号：6A6
荧光染料：其它
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类型: | 一抗(功能抗体） | 同型对照： | IgG2a, lambda |
浓度： | 1 mg/mL | 用法： | Assay-Dependent（功能检测） |
产品详细信息Description: This 6A6 monoclonal antibody reacts with mouse CD96, a cell adhesion receptor also known as TACTILE. A member of the Ig superfamily, CD96 is a single pass transmembrane protein consisting of three extracellular Ig-like domains and a proline/serine/threonine rich region. CD96 is expressed on resident monocytes and T cells at all developmental stages (including gammadelta T cells, thymocytes, and NK cells). In the mouse, this receptor is not expressed on B cells. Unlike in humans, mouse CD96 does not exist as alternative splice variants. Reports indicate that CD96 binds CD155/poliovirus receptor and Nectin-1 to mediate NK cell adhesion to target cells and cytotoxicity.This monoclonal antibody has been reported to block CD96 interaction with CD155 and Nectin-1.Applications Reported: This 6A6 antibody has been reported for use in functional assays.Applications Tested: This 6A6 antibody has been tested by flow cytometric analysis of mouse splenocytes. This can be used at less than or equal to 0.5 µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Storage and handling: Use in a sterile environment.Filtration: 0.2 µm post-manufacturing filtered.Purity: Greater than 90%, as determined by SDS-PAGE.Endotoxin Level: Less than 0.001 ng/µg antibody, as determined by LAL assay.Aggregation: Less than 10%, as determined by HPLC.靶标信息CD96 is a cell adhesion receptor also known as TACTILE. A member of the Ig superfamily, CD96 is a single pass transmembrane protein consisting of three extracellular Ig-like domains and a proline/serine/threonine rich region. CD96 is expressed on resident monocytes and T cells at all developmental stages (including gamma-delta T cells, thymocytes, and NK cells). In the mouse, this receptor is not expressed on B cells. Unlike in humans, mouse CD96 does not exist as alternative splice variants. Reports indicate that CD96 binds CD155/poliovirus receptor and Nectin-1 to mediate NK cell adhesion to target cells and cytotoxicity.仅用于科研。不用于诊断过程。
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