Goat anti Human ILF3 antibody
货号：VPA00549
规格：100 µL
价格：2890
产品类型：免疫组化一抗
品牌：Bio-Rad
抗原：ILF3
物种：人
宿主：山羊
抗体亚型：IgG
荧光染料：Purified
| 产品介绍 | | |
| Goat anti Human ILF3 antibodyrecognizes ILF3, also known as M-phase phosphoprotein 4, double-stranded RNA-binding protein 76, dsRNA binding protein NFAR-2/MPP4, interleukin enhancer binding factor 3, 90kD, nuclear factor associated with dsRNA, nuclear factor of activated T-cells 90 kDa or translational control protein 80.ILF3 gene encodes a double-stranded RNA (dsRNA) binding protein that complexes with other proteins, dsRNAs, small noncoding RNAs, and mRNAs to regulate gene expression and stabilize mRNAs. This protein was first discovered to be a subunit of the nuclear factor of activated T-cells (NFAT); a transcription factor required for T-cell expression of interleukin 2. NFAT is a heterodimer of 45 kDa and 90 kDa proteins, the larger of which is the product of ILF3. These proteins have been shown to affect the redistribution of nuclear mRNA to the cytoplasm. Knockdown of NF45 or NF90 protein retards cell growth; possibly by inhibition of mRNA stabilization. In contrast, an isoform (NF110) of ILF3 that is predominantly restricted to the nucleus has only minor effects on cell growth when its levels are reduced. Alternative splicing results in multiple transcript variants encoding distinct isoforms (provided by RefSeq, Nov 2008).Goat anti Human ILF3 antibody detects a band of 106 kDa. The antibody has been extensively validated for western blotting using whole cell lysates. |
| 产品详情 | | |
| Target Species | Human |
| Product Form | Purified IgG - liquid |
| Preparation | Goat polyclonal antibody purified by affinity chromatography. |
| Buffer Solution | TRIS buffered saline. |
| Preservative Stabilisers | 0.09% Sodium Azide (NaN3)0.5% Bovine Serum Albumin. |
| Immunogen | Peptide sequence C-QKPSYGSGYQSHQGQ |
| Acknowledgements | PrecisionAb is a trademark of Bio-Rad Laboratories. |
| Regulatory | For research purposes only |
| Guarantee | 12 months from date of despatch |
| 存储条件 | | |
| Store undiluted at -20°C, avoiding repeated freeze thaw cycles |
| 应用 | | |
| Application Name | Verified | Min Dilution | Max Dilution |
| Western Blotting | √ | | |
| This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls. |
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技术参数 产品应用 WB
产品类型 PrecisionAb Polyclonal
推荐用于 WB
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