Rabbit anti Human glutamate dehydrogenase 1 antibody
货号：VPA00667
规格：100μl
价格：3655
产品类型：免疫组化一抗
品牌：Bio-Rad
抗原：glutamate dehydrogenase 1
物种：人
宿主：兔
抗体亚型：IgG
荧光染料：Purified
| 产品介绍 | | |
| Rabbit anti Human glutamate dehydrogenase 1 antibodyrecognizes glutamate dehydrogenase 1, mitochondrial, also known as GDH 1, glutamate dehydrogenase (NAD(P)+), glutamate dehydrogenase 1, mitochondrial.The GLUD1 gene encodes glutamate dehydrogenase protein; a mitochondrial matrix enzyme that catalyzes the oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. This enzyme has an important role in regulating amino acid induced insulin secretion and activating mutations in GLUD1 are a common cause of congenital hyperinsulinism. This enzyme is allosterically activated by ADP and inhibited by GTP and ATP. The related glutamate dehydrogenase 2 gene on the human X-chromosome originated from GLUD1 via retrotransposition and encodes a soluble form of glutamate dehydrogenase. Multiple pseudogenes of GLUD1 are present in humans (provided by RefSeq, Sep 2009).Rabbit anti Human glutamate dehydrogenase antibody detects a band of 52 kDa. The antibody has been extensively validated for western blotting using whole cell lysates. |
| 产品详情 | | |
| Target Species | Human |
| Product Form | Purified IgG - liquid |
| Preparation | Rabbit polyclonal antibody purified by affinity chromatography. |
| Buffer Solution | Phosphate buffered saline. |
| Preservative Stabilisers | 0.09% Sodium Azide2% Sucrose |
| Immunogen | Synthetic peptide encompassing part of the N terminal region of human glutamate dehydrogenase 1 |
| Acknowledgements | PrecisionAb is a trademark of Bio-Rad Laboratories. |
| Regulatory | For research purposes only |
| Guarantee | 12 months from date of despatch. |
| 存储条件 | | |
| Store undiluted at -20°C, avoiding repeated freeze thaw cycles. |
| 应用 | | |
| Application Name | Verified | Min Dilution | Max Dilution |
| Western Blotting | √ | 1/1000 | |
| This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.Flow CytometryUse 10ul of the suggested working dilution to label 106cells or 100ul human whole blood. |
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技术参数 产品应用 wb
产品类型 多克隆抗体
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