Rabbit anti Human WASP antibody
货号:VPA00348
规格:100 µL
价格:2890
产品类型:免疫组化一抗
品牌:Bio-Rad
抗原:WASP
物种:人
宿主:兔
抗体亚型:IgG
荧光染料:Purified
产品介绍 | | |
Rabbit anti Human WASP antibodyrecognizes WASP, also known as eczema-thrombocytopenia, thrombocytopenia 1 (X-linked) and wiskott-Aldrich syndrome protein.The Wiskott-Aldrich syndrome (WAS) family of proteins share similar domain structure, and are involved in transduction of signals from receptors on the cell surface to the actin cytoskeleton. The presence of a number of different motifs suggests that they are regulated by a number of different stimuli, and interact with multiple proteins. WAS proteins, directly or indirectly, associate with the small GTPase, Cdc42, known to regulate formation of actin filaments, and the cytoskeletal organizing complex, Arp2/3.Wiskott-Aldrich syndrome, due to mutatations in the WAS gene, is a rare, inherited, X-linked, recessive disease characterized by immune dysregulation and microthrombocytopenia. The WAS gene product (WASP) is a cytoplasmic protein, expressed exclusively in hematopoietic cells, which show signaling and cytoskeletal abnormalities in WAS patients. A transcript variant arising as a result of alternative promoter usage, and containing a different 5′ UTR sequence, has been described (provided by RefSeq, Jul 2008).Rabbit anti Human WASP antibody detects a band of 60 kDa. Rabbit anti Human WASP antibody has been extensively validated for western blotting using whole cell lysates. |
产品详情 | | |
Target Species | Human |
Product Form | Purified IgG - liquid |
Preparation | Rabbit polyclonal antibody purified by affinity chromatography. |
Buffer Solution | Phosphate buffered saline. |
Preservative Stabilisers | 0.09% Sodium Azide (NaN3). |
Immunogen | KLH-conjugated synthetic peptide corresponding to aa 205-234 of human WASP |
Acknowledgements | PrecisionAb is a trademark of Bio-Rad Laboratories. |
Regulatory | For research purposes only |
Guarantee | 12 months from date of despatch |
存储条件 | | |
Store undiluted at -20°C, avoiding repeated freeze thaw cycles |
应用 | | |
Application Name | Verified | Min Dilution | Max Dilution |
Western Blotting | √ | | |
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls. |
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技术参数 产品应用 WB
产品类型 PrecisionAb Polyclonal
推荐用于 WB
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