Mouse anti Human YY1 antibody
货号:VMA00573
规格:100μl
价格:2780
产品类型:免疫组化一抗
品牌:Bio-Rad
抗原:YY1
物种:人
宿主:小鼠
抗体亚型:IgG1
克隆号: CD02/2B2
荧光染料:Purified
产品介绍 | | |
Mouse anti Human YY1 antibodyrecognizes the transcriptional repressor protein YY1, also known as INO80 complex subunit S or Yin and Yang 1 protein.The protein YY1 is a ubiquitously-expressed zinc finger transcription factor which can act as an activator or repressor of transcription under different circumstances (Galloway et al. 2017). In addition to transcriptional regulation, YY1 is involved with cell proliferation, chromatin remodeling and apoptosis. Many targets of YY1, for example ERBB2 and p53, are involved with cancer pathogenesis (Kaufhold et al. 2016). Accordingly, YY1 is overexpressed in multiple cancer types, and overexpression is correlated with poor prognosis (Cho and Bonavida 2017). YY1 may be inhibited by siRNA, proteasome inhibitors, and a variety of other factors. Inhibition of YY1 has been suggested as a potential target in cancer (Bonavida 2017). |
产品详情 | | |
Target Species | Human |
Product Form | Purified IgG - liquid |
Preparation | Mouse monoclonal antibody purified by affinity chromatography on Protein G from tissue culture supernatant. |
Buffer Solution | Phosphate buffered saline |
Preservative Stabilisers | 0.09% Sodium Azide (NaN3). |
Immunogen | E. coli-derived recombinant human YY1 (amino acids 1 - 414) |
Acknowledgements | PrecisionAb is a trademark of Bio-Rad Laboratories. |
Regulatory | For research purposes only |
Guarantee | 12 months from date of despatch. |
存储条件 | | |
Store undiluted at -20°C, avoiding repeated freeze thaw cycles. |
应用 | | |
Application Name | Verified | Min Dilution | Max Dilution |
Western Blotting | √ | 1/1000 | |
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.Flow CytometryUse 10ul of the suggested working dilution to label 106cells or 100ul human whole blood. |
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技术参数 产品应用 IP ;WB
产品类型 多克隆抗体
推荐用于 IP; WB
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