Mouse anti human CD45RA:StarBright Violet 440

货号：MCA88SBV440

规格：100 Tests/0.5ml

价格：3553

产品类型：流式抗体

品牌：Bio-Rad

抗原：CD45RA

物种：人

宿主：小鼠

抗体亚型：IgG1

克隆号： F8-11-13

荧光染料：StarBright Violet 440

类型:	单抗	同型对照：	IgG1
浓度：		用法：	5 µL/test(Flow)
免疫原性：	Human T lymphocytes

Mouse anti Human CD45RA antibody, clone F8-11-13recognizes the human CD45RA cell surface antigen.CD45 is a complex molecule existing in a number of isoforms. Antibodies recognizing a common epitope on all of these isoforms are termed CD45 whilst those recognizing only individual isoforms are termed CD45RA or CD45RO etc.Mouse anti Human CD45RA antibody, clone F8-11-13 reacts with the high molecular weight form of the leucocyte common antigen (LCA) expressed by B lymphocytes and a subset of T lymphocytes.Mouse anti Human CD45RA antibody, clone F8-11-13 is routinely tested in flow cytometry on human peripheral blood lymphocytes.

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参考文献：

1. Dalchau, R. & Fabre, J.W. (1981) Identification with a monoclonal antibody of a predominantly B lymphocyte-specific determinant of the human leukocyte common antigen. Evidence for structural and possible functional diversity of the human leukocyte common molecule.J Exp Med. 153 (4): 753-65.2. O'Grady, J.T.et al.(1994) CD40 expression in Hodgkin's disease.Am J Pathol. 144 (1): 21-6.3. Franitza, S.et al.(2002) TGF-beta1 enhances SDF-1alpha-induced chemotaxis and homing of naive T cells by up-regulating CXCR4 expression and downstream cytoskeletal effector molecules.Eur J Immunol. 32 (1): 193-202.4. Leigh, J.E.et al.(2006) Characterization of the immune status of CD8+ T cells in oral lesions of human immunodeficiency virus-infected persons with oropharyngeal Candidiasis.Clin Vaccine Immunol. 13 (6): 678-83.5. Hunt, L.et al.(2016) T cell subsets: an immunological biomarker to predict progression to clinical arthritis in ACPA-positive individuals.Ann Rheum Dis. 75 (10): 1884-9.6. Ibana, J.A.et al.(2012) The major CD8 T cell effector memory subset in the normal andChlamydia trachomatis-infected human endocervix is low in perforin.BMC Immunol. 13: 66.7. Ponchel, F.et al.(2014) An immunological biomarker to predict MTX response in early RA.Ann Rheum Dis. 73 (11): 2047-53.

技术参数

产品应用 Flow

产品类型 单克隆抗体

推荐用于 Flow

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