mouse anti human PAPILLOMAVIRUS 18 ONCOprotein E7
货号：MCA2820
规格：0.2 mg
价格：3018
产品类型：免疫组化一抗
品牌：Bio-Rad
抗原： PAPILLOMAVIRUS 18 ONCOprotein E7
物种：Virus
宿主：小鼠
抗体亚型：IgG1
克隆号：718-15
荧光染料：Purified
| 产品介绍 | | |
| Mouse anti Human Papillomavirus 18 Oncoprotein E7 antibody, clone 718-15recognizes the E7 oncoprotein of human papilloma virus 18. Human papillomavirus (HPV) is a diverse group of DNA-based viruses that infect skin and mucous membranes of humans and animals. Some HPV types are the causative agents of cervical cancer, with types 16 and 18 being particularly high-risk. The viral proteins E6 and E7 disrupts normal cell cycle regulation by interacting with p53 (a tumor-suppressing transcription factor) and Rb (retinoblastoma protein, also a tumor-supressor). E7 particularly binds to Rb and histone deacetylases, resulting in activation of the E2F genes, which code for a family of transcription factors. The viral proteins E6 and E7 might be of particular interest in the development of therapeutic vaccines, since they are expressed early in viral infection.Mouse anti Human Papillomavirus 18 Oncoprotein E7 antibody, clone 718-15 does not cross-react with the E7 protein of HPV-16. |
| 产品详情 | | |
| Target Species | Viral |
| Product Form | Purified IgG - liquid |
| Preparation | Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant |
| Buffer Solution | Phosphate buffered saline |
| Preservative Stabilisers | <0.1% Sodium Azide (NaN3) |
| Immunogen | Oncoprotein E7 from human papillomavirus 18. |
| Approx. Protein Concentrations | IgG concentration 1.0mg/ml |
| Regulatory | For research purposes only |
| Guarantee | 12 months from date of despatch |
| 存储条件 | | |
| This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended. |
| 应用 | | |
| Application Name | Verified | Min Dilution | Max Dilution |
| ELISA | √ | | |
| This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls. |
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技术参数 产品应用 ELISA;WB
产品类型 单克隆抗体
推荐用于 ELISA;WB
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