Rat anti Mouse CD120a antibody, clone HM104
货号:MCA2078PET,MCA2078PE
规格:25 Tests,100 Tests
价格:1488,8177
产品类型:流式抗体
品牌:Bio-Rad
抗原:CD120a
物种:小鼠
宿主:大鼠
抗体亚型:IgG2a
克隆号:HM104
荧光染料:PE
产品介绍 | | |
Rat anti Mouse CD120a antibody, clone HM104recognizes an extracellular region of mouse CD120a, also known as TNF receptor type I (TNFR1). TNFR1 is an ubiquitously expressed transmembrane glycoprotein and member of the tumor necrosis factor receptor (TNFR) superfamily, which plays a key role in regulating the inflammatory response, acting as a receptor for tumor necrosis factor alpha (TNF-alpha) and lymphotoxin-alpha (TNF-beta).CD120a also plays a role in apoptosis, cytokine induction, cell differentiation, tumor necrosis and early stages of graft-versus-host disease, and its soluble form sTNFR1, acts as an inhibitor of TNF-alpha induced responses by acting as a decoy receptor. |
产品详情 | | |
Target Species | Mouse |
Product Form | Purified IgG conjugated to R. Phycoerythrin (RPE) - liquid |
Reconstitution | Reconstitute with 1.0 ml distilled waterCare should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. Bio-Rad recommend that the vial is gently mixed after reconstitution. |
Preparation | Purified IgG prepared by ion exchange chromatography. |
Buffer Solution | Phosphate buffered saline |
Preservative Stabilisers | Pack Size: 100 Tests<0.1% Sodium Azide (NaN3)0.05% Bovine Serum AlbuminPack Size: 25 Tests<0.1% Sodium Azide (NaN3)1% Bovine Serum Albumin |
Fusion Partners | Spleen cells from immunized BALB/c mice were fused with cells of the X63/Ag8.653 mouse myeloma cell line |
Max Ex/Em | Fluorophore | Excitation Max (nm) | Emission Max (nm) |
RPE 488nm laser | 496 | 578 |
Regulatory | For research purposes only |
Guarantee | 6 months from date of despatch |
存储条件 | | |
Prior to reconstitution store at +4℃. Following reconstitution store at +4℃.DO NOT FREEZE.This product should be stored undiluted. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use. |
应用 | | |
Application Name | Verified | Min Dilution | Max Dilution |
Flow Cytometry | √ | | |
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls. |
推荐产品 |
Description | Product Code | Applications | Pack Size |
Rat IgG2a Negative Control:RPE | MCA1212PE | F | 100 Tests |
文献 |
1.Pearl-Yafe, M.et al.(2010) Tumor necrosis factor receptors support murine hematopoietic progenitor function in the early stages of engraftment.Stem Cells. 28 (7): 1270-80.2.Nakagawa, J.et al.(2007) TNF expressed by tumor-associated macrophages, but not microglia, can eliminate glioma.Int J Oncol. 30 (4): 803-11. |
技术参数 产品应用 Flow
产品类型 Monoclonal Antibody
推荐用于 Flow
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