Mouse anti Human CD222 antibody, clone MEM-238
货号：MCA2048F
规格：0.1 mg
价格：3145
产品类型：流式抗体
品牌：Bio-Rad
抗原：CD222
物种：人
宿主：小鼠
抗体亚型：IgG1
克隆号：MEM-238
荧光染料：FITC
| 产品介绍 | | |
| Mouse anti Human CD222 antibody, clone MEM-238recognizes human CD222, a 250 kDa transmembrane protein originally identified as the IGF II receptor. CD222 is ubiquitously expressed and is involved with internalization of a variety of ligands.Mouse anti Human CD222 antibody, clone MEM-238 recognizes an epitope located in the region between extracellular domains 2 and 5 (aa 192-697) of CD222 (Robertset al.2010).CD222 is primarily expressed intracellularly with a small percentage of molecules being located at the cell surface (5 - 10%). |
| 产品详情 | | |
| Target Species | Human |
| Product Form | Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC) - liquid |
| Preparation | Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant. |
| Buffer Solution | Phosphate buffered saline |
| Preservative Stabilisers | 0.09%Sodium Azide |
| Max Ex/Em | Fluorophore | Excitation Max (nm) | Emission Max (nm) |
| FITC | 490 | 525 |
| Approx. Protein Concentrations | IgG concentration 0.1mg/ml |
| Regulatory | For research purposes only |
| Guarantee | 12 months from date of despatch |
| 存储条件 | | |
| This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended. |
| 应用 | | |
| Application Name | Verified | Min Dilution | Max Dilution |
| Immunofluorescence | √ | 1/10 | |
| This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls. |
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| 文献 |
| 1.Roberts, R.C.et al.(2010) Mistargeting of SH3TC2 away from the recycling endosome causes Charcot-Marie-Tooth disease type 4C.Hum Mol Genet. 19: 1009-18.2.Adachi, A.et al.(2010) Golgi-associated GSK3beta regulates the sorting process of post-Golgi membrane trafficking.J Cell Sci. 123: 3215-25.3.Godar, S.et al. (2002) CD222 (Mannose-6 phosphate / insulin-like growth factor II-receptor) Summary and Workshop Report.In Leucocyte Typing VII: White Cell Differentiation Antigens. Edited by Mason, D.et al.Oxford University Press. pp482-485.4.Rezgui, D.et al.(2009) Structure and function of the human Gly1619Arg polymorphism of M6P/IGF2R domain 11 implicated in IGF2 dependent growth.J Mol Endocrinol. 42: 341-56. |
技术参数 产品应用 Flow
产品类型 Monoclonal Antibody
推荐用于 Flow
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