Human anti Human HbA1c antibody, clone AbD15792_IgG1
货号：HCA219
规格：0.1 mg
价格：2576
产品类型：免疫组化一抗
品牌：Bio-Rad
抗原：HbA1c
物种：其它
宿主：人
抗体亚型：IgG1
克隆号：AbD15792_IgG1
荧光染料：其它
| 产品介绍 | | |
| Human anti Human HbA1c antibody, clone AbD15792_IgG1recognizes HbA1c, hemoglobin glycated at the N-terminal valine of the hemoglobin β chain. It does not bind to non-glycated hamoglobin. Besides binding to the normal glycated haemoglobin. Human anti Human HbA1c antibody, clone AbD15792_IgG1 also recognizes the glycated hemoglobin variants HbD and HbE, but does not recognise the HbS or HbC variants. Elevated HbF is not detected due to the absence of the hemoglobin β chain.The measurement of HbA1c levels is used to identify the average plasma glucose concentration. In diabetes mellitus, higher levels of HbA1c have been associated with cardiovascular disease and other diseases. Levels of more than 6.5% HbA1c (48 mmol/mol) are used as a criterion to diagnose diabetes. This antibody is also available in a Fab format (HCA200). |
| 产品详情 | | |
| Target Species | Human |
| Product Form | Human IgG1 antibody selected from the HuCAL® phage display library and expressed in a human cell line.This antibody is supplied as a liquid. |
| Preparation | Purified IgG prepared by affinity chromatography on Protein A |
| Buffer Solution | Phosphate buffered saline |
| Preservative Stabilisers | 0.01% Thiomersal |
| Immunogen | The immunogens used in the generation of this antibody were:A glycated peptide, corresponding to N-terminal 9 amino acids of haemoglobin beta chain coupled to the carrier proteins BSA and TRFPurified HbA1c |
| Affinity | The affinity of this antibody, as a monovalent fab measured against the immunogen, was measured as KD=7 nM by real time, label-free molecular interaction analysis using HbA1c-BSA and HbA1c-TRF conjugates as immobilized antigen.The affinity of this antibody, as a monovalent fab measured against purified HbA1c, was measured as KD=54 nM by real time, label-free molecular interaction analysis using full length HbA1c as immobilized antigen |
| Approx. Protein ConcePurityntrations | Total protein concentration 0.5 mg/ml |
| Acknowledgements | This product and/or its use is covered by claims of U.S. patents, and/or pending U.S. and non-U.S. patent applications owned by or under license to Bio-Rad Laboratories, Inc. See bio-rad.com/en-us/trademarks for details. |
| Regulatory | For research purposes only |
| Guarantee | 12 months from date of despatch |
| 存储条件 | | |
| This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended. |
| 应用 | | |
| Application Name | Verified | Min Dilution | Max Dilution |
| ELISA | √ | | |
| This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls. |
| 产品推荐 |
| Description | Product Code | Applications | Pack Size |
| Human anti Human HbA1c | HCA179 | E | 0.1mg |
技术参数 产品应用 elisa
产品类型 单克隆抗体
推荐用于 elisa
©
Bio-Rad伯乐代理官网-伯乐抗体-伯乐层析Aminex色谱柱是专业的授权总代理区域代理经销平台。
© 如需询价，请加客服QQ：1749072012 、客服微信：jinshanbio，或发送邮件到1749072012@qq.com
© 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务，数据资源基于CC协议。
© 本文地址：
https://biorod.cn/thread-34044.htm
QQ:1749072012