产品介绍 |
| Rabbit anti p38 alpha MAPK antibodyrecognizes mitogen-activated protein kinase p38 alpha (p38-alpha MAPK), also known as MAP kinase 14 (MAPK14) and stress activated protein kinase 2a (SAPK2a). p38 alpha is a member of the p38 MAPK serine/threonine kinase protein family, which also includes p38-beta (MAPK11), p38-gamma (MAPK12) and p38-delta (MAPK13) (Cargnello and Roux 2011).p38 alpha MAPK becomes activated in response to a variety of stimuli, which include inflammatory cytokines and oxidative stress (Cargnello and Roux 2011). p38 alpha MAPK plays an essential role in mediating inflammation by regulating the expression of tumor necrosis factor alpha (TNF alpha) and interleukin 1 (IL-1) (Dhillon et al. 2007). p38 MAPK proteins have been implicated in cancer development and p38 alpha MAPK has been proposed to act as a tumor suppressor (Dhillon et al. 2007). |
产品详情 |
Target Species | Mouse |
Species Cross-Reactivity | Target SpeciesCross Reactivity |
| Rat √ |
| Human √ |
| N.B. Antibody reactivity and working conditions may vary between species. |
Product Form | Purified IgG - liquid |
Preparation | Purified IgG prepared by affinity chromatography |
AntiserumPreparation | Antiserum to p38 alpha MAPK was raised by repeated immunisation of rabbits with highly purified antigen |
Buffer Solution | Phosphate buffered saline |
Preservative Stabilisers | 0.1% Sodium Azide (NaN3)0.2% Gelatin |
Immunogen | Peptide mapping to the carboxy terminus of mouse p38 alpha MAPK and sharing 100% homology with the human sequence |
Approx. Protein Concentrations | IgG concentration 0.2 mg/ml |
Regulatory | For research purposes only |
Guarantee | 12 months from date of despatch |
存储条件 |
| Store at +4℃. DO NOT FREEZE.This product should be stored undiluted. Should this product contain a precipitate we recommend microcentrifugation before use. |
应用 |
Application Name | Verified | Min Dilution | Max Dilution |
Western Blotting | √ | 1/200 | |
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.- Western Blotting
- Rabbit anti p38 alpha MAPK recognizes a band of approximately 38 kDa when run under reducing conditions
|
二抗相关产品 |
Description | Product Code | Applications | Pack Size |
Goat anti Rabbit IgG (Fc):Biotin | STAR121B | E WB | 1 mg |
Goat anti Rabbit IgG (Fc):FITC | STAR121F | F | 1 mg |
Goat anti Rabbit IgG (Fc):HRP | STAR121P | E WB | 1 mg |
Goat anti Rabbit IgG (H/L):HRP | STAR124P | C E WB | 1 mg |
Sheep anti Rabbit IgG:FITC | STAR34B | C F | 1 mg |
Sheep anti Rabbit IgG:RPE | STAR35A | F | 1 ml |
相关产品 |
Description | Product Code | Applications | Pack Size |
TidyBlot Western Blot Detection Reagent:HRP | STAR209P | WB* | 0.5 ml |
QQ:1749072012