Goat anti Human FOXP2 antibody
货号：AHP2020
规格：0.1 mg
价格：6095
产品类型：免疫组化一抗
品牌：Bio-Rad
抗原： FOXP2
物种：人
宿主：山羊
抗体亚型：IgG
荧光染料：Purified
| 产品介绍 | | |
| Goat anti Human FOXP2 antibodyrecognizes Forkhead box protein P2, also known as FOXP2, CAG repeat protein 44 or Trinucleotide repeat-containing gene 10 protein. FOXP2 is a 715 amino acid ~80 kDa nuclear transcriptional repressor with a role in brain and lung development.Mutations in the FOXP2 gene has been identified Speech-language disorder 1 (SPCH1), a disorder characterized by severe orofacial dyspraxia with speech impairment (Laiet al.2001).Multiple potential isoforms of FOXP2 generated by alternative splicing have been described. Goat anti Human FOXP2 antibody (AHP2020) is expected to recognize the canonical isoform 1 and also isoforms 3 and 9. However the antibody is not expected other isoforms which lack the c-terminal region (UniProt : 015409). |
| 产品详情 | | |
Target Species | Human |
| Species Cross-Reactivity | Target Species | Cross Reactivity |
| Mammals | Expected from Sequence |
| N.B. Antibody reactivity and working conditions may vary between species. |
Product Form | Purified IgG - liquid |
Antiserum Preparation | Antiserum to human FOXP2 (CT) was raised by repeated immunisation of goats with highly purified antigen. Purified IgG was prepared by affinity chromatography. |
Buffer Solution | TRIS buffered saline |
Preservative Stabilisers | 0.02% Sodium Azide (NaN3)0.5% Bovine Serum Albumin |
Immunogen | Peptide with sequence C-REIEEEPLSEDLE from the C Terminus of FOXP2. |
| Approx. Protein Concentrations | IgG concentration 0.5 mg/ml |
Regulatory | For research purposes only |
Guarantee | 12 months from date of despatch |
| 存储条件 | | |
| Prior to reconstitution store at -20°C.After reconstitution store at -20°C.This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. |
| 应用 | | |
Application Name | Verified | Min Dilution | Max Dilution |
| ELISA | √ | 1/32000 | |
| Western Blotting | √ | 0.5 | 1.5ug/ml |
| This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.Western BlottingAHP2020 detects a band of approximately 80kDa in human cerebellum cell lysates. |
| 数据 |
| Western blotting analysis of human cerebellum lysate (35μg protein in RIPA buffer) probed with Goat anti Human FOXP2 antibody (AHP2020) at 0.5μgml-1. Primary incubation was 1 hour. Signal was detected by chemiluminescence. |
| 文献 |
| 1. Vernes, S.C.et al.(2007) High-throughput analysis of promoter occupancy reveals direct neural targets of FOXP2, a gene mutated in speech and language disorders.Am J Hum Genet. 81 (6): 1232-50.2. Vernes, S.C.et al.(2006) Functional genetic analysis of mutations implicated in a human speech and language disorder.Hum Mol Genet. 15 (21): 3154-67. |
技术参数 产品应用 E;WB
产品类型 Polyclonal Antibody
推荐用于 E;WB
©
Bio-Rad伯乐代理官网-伯乐抗体-伯乐层析Aminex色谱柱是专业的授权总代理区域代理经销平台。
© 如需询价，请加客服QQ：1749072012 、客服微信：jinshanbio，或发送邮件到1749072012@qq.com
© 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务，数据资源基于CC协议。
© 本文地址：
https://biorod.cn/thread-34925.htm
QQ:1749072012