Rabbit anti Human Cyclin E antibody
货号：AHP1245
规格：50 µl
价格：4191
产品类型：免疫组化一抗
品牌：Bio-Rad
抗原：Cyclin E
物种：其它
宿主：兔
抗体亚型：IgG
荧光染料：Purified
| 产品介绍 | | |
| Rabbit anti Human Cyclin E antibodydetects cyclin E, a nuclear protein which is the regulatory subunit of cyclin dependent kinase 2 (Cdk2), and controls S phase entry in cells. Cyclin E follows a cyclic pattern of expression during the cell cycle, with highest expression at the G1-S boundary.Although cyclin E has an important physiological role in normal cell division, recent reports suggest this function is redundant, and its key functions occur as cells exit quiescence, and in endoreduplication.Cyclin E is tightly regulated during normal cell cycles, but is often deregulated in carcinomas, lymphoma, and leukaemia. |
| 产品详情 | | |
| Target Species | Human |
| Product Form | Serum - liquid |
| Antiserum Preparation | Antisera to cyclin E were raised by repeated immunisations of rabbits with highly purified antigen. |
| Buffer Solution | <0.1% Sodium Azide (NaN3) |
| Immunogen | Synthetic peptide corresponding to a region near the C-terminus of human Cyclin E conjugated to KLH. |
| Regulatory | For research purposes only |
| Guarantee | 12 months from date of despatch |
| 存储条件 | | |
| This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended. |
| 应用 | | |
| Application Name | Verified | Min Dilution | Max Dilution |
| ELISA | √ | | 1/2000 |
| This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls. |
| 二抗 |
| Description | Product Code | Applications | Pack Size |
| Goat anti Rabbit IgG (Fc):Biotin | STAR121B | E,WB | 1mg |
| Goat anti Rabbit IgG (H/L):HRP | STAR124P | C,E,WB | 1mg |
| 文献 |
| 1.Hwang, H.C. & Clurman, B.E. (2005) Cyclin E in normal and neoplastic cell cycles.Oncogene. 24 (17): 2776-86.2.Zhang, H. (2007) Life without kinase: cyclin E promotes DNA replication licensing and beyond.Mol Cell. 25 (2): 175-6. |
技术参数 产品应用 elisa;wb
产品类型 Polyclonal Antibody
推荐用于 elisa;wb
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