Sheep anti Rat endothelin B receptor antibody
货号：AAR43
规格：0.1 mg
价格：2992
产品类型：免疫组化一抗
品牌：Bio-Rad
物种：大鼠
宿主：Sheep
抗体亚型：IgG
荧光染料：Purified
| 产品介绍 | | |
| Sheep anti Rat endothelin B receptor antibodyrecognizes an epitope within the C-terminal (CT) region of endothelin B receptor (ET-B), a widely distributed transmembrane protein and member of the G-protein coupled receptor 1 family, which acts as a non-specific receptor for endothelin 1, 2, and 3, and mediates its action by G protein association and activation of a phosphatidylinositol-calcium second messenger system. Sheep anti Rat endothelin B receptor antibody (AAR43) recognizes epitopes on the cytoplasmic side of the receptor and therefore the cell membrane must be permeable to the antibody. AAR43 does not block the binding of endothelins.Sheep anti Rat endothelin B receptor antibody (AAR43) is suitable for use in immunocytochemistry on acetone fixed cells. |
| 产品详情 | | |
| Target Species | Rat |
| Product Form | Purified IgG - liquid |
| Species Cross-Reactivity | Target Species | Cross Reactivity |
| Mouse | √ |
| Human | √ |
| N.B. Antibody reactivity and working conditions may vary between species. |
| Antiserum Preparation | Antiserum to rat ET-B (CT) was raised by repeated immunisation of sheep with highly purified antigen. Purified IgG was prepared by affinity chromatography. |
| Buffer Solution | Phosphate buffered saline |
| Preservative Stabilisers | <0.1% Sodium Azide (NaN3) |
| Immunogen | Keyhole limpet haemocyanin (KLH) conjugated C-terminal peptide KANDHGYDNFRSSNN corresponding to amino acids 424 to 437 of rat endothelin B receptor. |
| Approx. Protein Concentrations | IgG concentration 1.41mg/ml |
| Regulatory | For research purposes only |
| Guarantee | 12 months from date of despatch |
| 存储条件 | | |
| Store at +4℃. DO NOT FREEZE.This product should be stored undiluted. Should this product contain a precipitate we recommend microcentrifugation before use. |
| 应用 | | |
| Application Name | Verified | Min Dilution | Max Dilution |
| Immunocytochemistry | √ | | |
| This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls. |
| 二抗 |
| Description | Product Code | Applications | Pack Size |
| Rabbit anti Sheep IgG (H/L):Biotin | 5184-2304 | F,E | 0.5mg |
| Donkey anti Sheep/Goat IgG:DyLight®488 | STAR88D488GA | F,IF | 0.5mg |
技术参数 产品应用 if
产品类型 Polyclonal Antibody
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