Goat anti Respiratory Syncytial Virus:Biotin
货号：7950-0104
规格：1 ml
价格：4973
产品类型：免疫组化一抗
品牌：Bio-Rad
抗原：Respiratory Syncytial Virus
物种：Viral
宿主：山羊
抗体亚型：IgG
荧光染料：Biotin
| 产品介绍 | | |
| Goat anti respiratory syncitial virus polyclonal antibodyrecognizes respiratory syncytial virus (RSV) a negative-sense, single-stranded RNA virus and member of theParamyxoviridaefamily. RSV causes respiratory tract infections in patients of all ages, but particularly affects infants and the immunosuppressed.RSV encodes three envelope glycoproteins, a small hydrophobic (SH) protein of unknown function, a glycoprotein (G) known as the attachment protein, and a fusion (F) protein. The F protein directs fusion of viral and cellular membranes, resulting in viral penetration, and can lead to the formation of syncytia.The F protein is thought to be the principal antigen responsible for inducing an immune response.Goat anti respiratory syncitial virus does not react with Parainfluenza 1-3, Influenza A and B, Adenovirus or uninfected HEp-2 or WI-38 cells. Goat anti respiratory syncitial virus polyclonal antibody is neutralizing and reacts well with bovine isolates. |
| 产品详情 | | |
Target Species | Viral |
Product Form | Purified IgG conjugated to Biotin - liquid |
Buffer Solution | Phosphate buffered saline |
Preservative Stabilisers | 0.1% Sodium Azide (NaN3) |
Approx. Protein Concentrations | IgG concentration 4.0 mg/ml |
Immunogen | Human RSV isolate. |
Regulatory | For research purposes only |
Guarantee | 12 months from date of despatch |
| 存储条件 | | |
| This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended. |
| 应用 | | |
Application Name | Verified | Min Dilution | Max Dilution |
ELISA | √ | | |
Functional Assays | √ | | |
Immunohistology - Frozen | √ | | |
| This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls. |
| 文献 |
| 1. Culley, F.J.et al.(2006) Role of CCL5 (RANTES) in viral lung disease.J Virol. 80: 8151-7.2. Numata, M.et al.(2010) Pulmonary surfactant phosphatidylglycerol inhibits respiratory syncytial virus-induced inflammation and infection.Proc Natl Acad Sci U S A. 107: 320-5.3. Roux, X.et al.(2008) Sub-nucleocapsid nanoparticles: a nasal vaccine against respiratory syncytial virus.PLoS One. 3: e1766.4. Olszewska, W.et al.(2011) Antiviral and lung protective activity of a novel RSV fusion inhibitor in a mouse model.Eur Respir J. 38: 401-8.5. Fonceca AMet al.(2012) Primary airway epithelial cultures from children are highly permissive to respiratory syncytial virus infection.Thorax. 67 (1): 42-8.6. Ryzhakov, G.et al.(2011) IL-17 Boosts Proinflammatory Outcome of Antiviral Response in Human Cells.J Immunol. 187: 5357-62.7. Fricke Jet al.(2013) p38 and OGT sequestration into viral inclusion bodies in cells infected with human respiratory syncytial virus suppresses MK2 activities and stress granule assembly.J Virol. 87 (3): 1333-47. |
技术参数 产品应用 IHC(F);ELISA;FN
产品类型 Polyclonal Antibody
推荐用于 IHC(F);ELISA;FN
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