Mouse anti peptidoglycan antibody, clone 3F6B3
货号：7263-1006
规格：0.1 ml
价格：5075
产品类型：免疫组化一抗
品牌：Bio-Rad
物种：其它
宿主：小鼠
抗体亚型：其它
克隆号：3F6B3
荧光染料：Purified
| 产品介绍 | | |
| Mouse anti peptidoglycan antibody, clone 3F6B3recognizes the 3D polymer complex structure of peptidoglycan (PG). In a competitive immunoassay format, several compounds were found to be ineffective as inhibitors; muramyldipeptide, N-acetylglucosamine, chitin and acid hydrolyzed chitin. The epitope appears to consist of discontinuous glycan and/or amino acid residues. |
| 产品详情 | | |
| Target Species | Bacterial |
| Product Form | Ascitic Fluid - raw |
| Preparation | Purified IgG prepared by affinity chromatography on Protein A |
| Buffer Solution | Phosphate/Citrate buffered saline |
| Preservative Stabilisers | None present. |
| Immunogen | This antibody was raised against insoluble peptidoglycan obtained by TCA-heat and ethanol extraction ofStreptococcus mutansBHT cells. |
| Approx. Protein Concentrations | IgG concentration 1.0 mg/ml |
| Regulatory | For research purposes only |
| Guarantee | 12 months from date of despatch |
| 存储条件 | | |
| Store at -20℃ only.Storage in frost-free freezers is not recommended.This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. |
| 应用 | | |
| Application Name | Verified | Min Dilution | Max Dilution |
| ELISA | √ | | |
| This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls. |
| 文献 |
| 1.Miklossy, J.et al.(2004)Borrelia burgdorferipersists in the brain in chronic lyme neuroborreliosis and may be associated with Alzheimer disease.J. Alzheimer's Dis. 6: 639-49.2.Wu, L.et al.(2007) Bacterial peptidoglycan breaks down intestinal tolerance via mast cell activation: the role of TLR2 and NOD2.Immunol Cell Biol. 85: 538-45.3.Rennemeier, C.et al.(2007) Thrombospondin-1 promotes cellular adherence of gram-positive pathogens via recognition of peptidoglycan.FASEB J. 21 (12): 3118-32.4.Schweitzer, M.H.et al.(2016) Testing the Hypothesis of Biofilm as a Source for Soft Tissue and Cell-Like Structures Preserved in Dinosaur Bone.PLoS One. 11 (2): e0150238.5.Miklossy Jet al.(2008) Persisting atypical and cystic forms ofBorrelia burgdorferiand local inflammation in Lyme neuroborreliosis.J Neuroinflammation. 5: 40.6.Robertson, J.et al.(2016) Intestinal APCs of the endogenous nanomineral pathway fail to express PD-L1 in Crohn's disease.Sci Rep. 6: 26747.7.Miklossy, J. (2016) Bacterial Amyloid and DNA are Important Constituents of Senile Plaques: Further Evidence of the Spirochetal and Biofilm Nature of Senile Plaques.J Alzheimers Dis. 53 (4): 1459-73.8.Miklossy, J.et al.(2008) Type 2 Diabetes: Local Inflammation and Direct Effect of Bacterial Toxic ComponentsThe Open Pathology Journal. 2 (1): 86-95. |
技术参数 产品应用 elisa
产品类型 Monoclonal Antibody
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