Rat anti mouse Interleukin 17 antibody, clone TC11-8H4
货号：1021401
规格：0.5 mg
价格：5423
产品类型：免疫组化一抗
品牌：Bio-Rad
抗原：Interleukin 17
物种：小鼠
宿主：大鼠
抗体亚型：IgG1
克隆号：TC11-8H4
荧光染料：Purified
| 产品介绍 | | |
| Rat anti mouse Interleukin 17 antibody, clone TC11-8H4recognizes mouse Interleukin 17, a 32kDa disulfide-linked homodimer consisting of two 136 amino acid chains, which belong to the IL-17 family (classified as IL-17A to IL-17F), and signal through the IL-17 receptor (IL-17R/CDw217).IL-17 is produced primarily by activated CD4+ T cells and induces a variety of target cells to secrete inflammatory cytokines, including IL-1beta, IL-6, TNFalpha, IFNgamma and granulocyte colony-stimulating factor, as well as synergizing with other inflammatory cytokines and agonists. The role of IL-17 in bone metabolism has become a focus area for studies into Rheumatoid Arthritis, in which levels of IL-17 are significantly increased and may contribute to bone destruction (Chabaudet al.2000).Rat anti mouse interleukin-17 antibody has been successfully used for the identification of IL-17 secreting cells in a murine anti-tumor immunity model by ELISPOT analysis (Yuet al.2013) |
| 产品详情 | | |
| Target Species | Human |
| Product Form | Purified IgG - liquid |
| Buffer Solution | Borate buffered saline |
| Preservative Stabilisers | None present. |
| Immunogen | Recombinant mouse IL-17 expressed inE. coli |
| Approx. Protein Concentrations | 0.5 mg/ml |
| Regulatory | For research purposes only |
| Guarantee | Guaranteed until date of expiry. Please see product label. |
| 存储条件 | | |
| Store at -20℃ only.Storage in frost-free freezers is not recommended.This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. |
| 应用 | | |
| Application Name | Verified | Min Dilution | Max Dilution |
| ELISA | √ | | |
| This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls. |
| 二抗 |
| Description | Product Code | Applications | Pack Size |
| Goat anti Rat IgG:Alk. Phos. (Mouse Adsorbed) | STAR131A | C,E,P,WB | 1 ml |
| Rabbit F(ab')2 anti Rat IgG:FITC | STAR17B | F | 1mg |
技术参数 产品应用 Elisa
产品类型 Monoclonal Antibody
推荐用于 Elisa
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