| 产品介绍 | | |
| Goat anti Human IgA antibodyrecognizes the heavy chain of human IgA as demonstrated by ELISA and Flow cytometry. IgA is the major catagory of antibody present in mucosal secretions and acts as a first line of defense against inhaled or ingested pathogens at the mucosal interface. IgA is also present in serum where it acts to eliminate pathogens via interaction with FcαR, also known as CD89. (Woofet al.2004).Biotinylated Goat anti Human IgA antibody (205008) has been cross-adsorbed against human IgD, IgG and IgM to ensure class specificity. |
| 产品详情 | | |
Target Species | Human |
Product Form | Purified IgG conjugated to R. Phycoerythrin (RPE) - liquid |
Preparation | Purified IgG prepared by affinity chromatography on pooled human IgA |
Buffer Solution | Phosphate buffered saline |
Preservative Stabilisers | <0.1% Sodium Azide (NaN3)Stabilizing agent (sucrose) |
Approx. Protein Concentrations | 0.5 mg/ml |
Immunogen | Human IgA. |
Regulatory | For research purposes only |
Guarantee | Guaranteed until date of expiry. Please see product label. |
Max Ex/Em | 496/578 |
| 存储条件 | | |
| +4ºC DO NOT FREEZEThis product is photosensitive and should be protected from light. |
| 应用 | | |
Application Name | Verified | Min Dilution | Max Dilution |
Flow Cytometry | √ | | |
| This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls. |
| 相关产品 |
Description | Product Code | Applications | Pack Size |
Human Seroblock | BUF070A | Flow | 50 Test |
Human Seroblock | BUF070B | Flow | 200 Test |
| 文献 |
| 1. Wright, A.K.et al.(2012) Human Nasal Challenge withStreptococcus pneumoniaeIs Immunising in the Absence of Carriage.PLoS Pathog. 8: e1002622.2. Pennington, S.H.et al.(2016) Polysaccharide-specific Memory B-cells Predict Protection Against Experimental Human Pneumococcal Carriage.Am J Respir Crit Care Med. Jul 12. [Epub ahead of print]3. Turner, P.J.et al.(2020) Differences in nasal immunoglobulin A responses to influenza vaccine strains after live attenuated influenza vaccine (LAIV) immunization in children.Clin Exp Immunol. 199 (2): 109-118.4. Cole, M.E.et al.(2021) Pre-existing influenza-specific nasal IgA or nasal viral infection does not affect live attenuated influenza vaccine immunogenicity in children.Clin Exp Immunol. 204 (1): 125-133. |
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