Recombinant Human FGF-4 Synonyms:Fibroblast Growth Factor-4, HST-1, transforming protein KS3, HBGF-4

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Description:

FGF-4 is a heparin binding growth factor that is a member of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-4 signals through the FGFR 1c, 2c, 3c, and 4. Recombinant human FGF-4 is a 19.7 kDa protein consisting of 182 amino acid residues.AA Sequence:GRGGAAAPTA PNGTLEAELE RRWESLVALS LARLPVAAQP KEAAVQSGAG DYLLGIKRLR RLYCNVGIGF HLQALPDGRI GGAHADTRDS LLELSPVERG VVSIFGVASR FFVAMSSKGK LYGSPFFTDE CTFKEILLPN NYNAYESYKY PGMFIALSKN GKTKKGNRVS PTMKVTHFLP RLSource:E.coliPurity:Greater than 95% by SDS-PAGE gel and HPLC analyses.Biological Activity:TheED₅₀as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF-receptors is ≤ 0.5 ng/ml, corresponding to a specific activity of ≥ 2 x 10⁶units/mg.Cross Reactivity:Mouse, Rat, Human, N/A, PigResearch Interests:

	Angiogenesis/ Cardiovascular		FGF Superfamily
	Proliferation		Stem Cells & Differentiation

Country of Origin:USAResearch Use Only. Not for use in diagnostic or therapeutic procedures.