Applications

FA

Synonyms:

3-MA, N(3)-methyladenine

Formulation:

Crystalline solid

Chemical Name:

3-methylpurin-6-amine

Molecular Formula:

C₆H₇N₅

Molecular Weight:

149.2

CAS Number

5142-23-4

Purity:

≥98%

Storage Conditions:

Product should be kept at -20°C.

References:

Seglen, P. O., & Gordon, P. B. (1982). 3-Methyladenine: specific inhibitor of autophagic/lysosomal protein degradation in isolated rat hepatocytes.Proceedings of the National Academy of Sciences,79(6), 1889-1892.

Wu, Y. T., Tan, H. L., Shui, G., Bauvy, C., Huang, Q., Wenk, M. R., ... & Shen, H. M. (2010). Dual role of 3-methyladenine in modulation of autophagy via different temporal patterns of inhibition on class I and III phosphoinositide 3-kinase.Journal of Biological Chemistry,285(14), 10850-10861.

CARO, L. H. P., PLOMP, P. J., WOLVETANG, E. J., KERKHOF, C., & MEIJER, A. J. (1988). 3‐Methyladenine, an inhibitor of autophagy, has multiple effects on metabolism.European Journal of Biochemistry,175(2), 325-329.