5(S),6(R)-Lipoxin A4

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5(S),6(R)-Lipoxin A4

货号:8968653-100,8968653-25

规格:100ug,100 ug

价格:7205,2035

产品类型:小分子化合物

品牌:Biogems

Lipoxin A4 is a potent kinase C activator that inhibits the cytotoxicity of NK cells. It is equipotent to leukotriene B4 that is involved in the inflammation response and capable of inducing the adhesion and activation of leukocytes on the endothelium.

其它信息:

Applications

FA

Synonyms:

15-epi-lipoxin A4, 5,6,15-trihydroxy-7,9,11,13-eicosatetraenoic acid, LXA4, 5(S),6(R)-Lipoxin A4

Formulation:

Ethanol Solution

Chemical Name:

(5S,6R,7E,9E,11Z,13E,15S)-5,6,15-trihydroxyicosa-7,9,11,13-tetraenoic acid

Molecular Formula:

C20H32O5

Molecular Weight:

352.5

CAS Number

89663-86-5

Purity:

≥95%

Storage Conditions:

Product should be kept at -80°C.

References:

Levy, B. D., De Sanctis, G. T., Devchand, P. R., Kim, E., Ackerman, K., Schmidt, B. A., ... & Serhan, C. N. (2002). Multi-pronged inhibition of airway hyper-responsiveness and inflammation by lipoxin A4.Nature medicine,8(9), 1018-1023.

Machado, F. S., Johndrow, J. E., Esper, L., Dias, A., Bafica, A., Serhan, C. N., & Aliberti, J. (2006). Anti-inflammatory actions of lipoxin A4 and aspirin-triggered lipoxin are SOCS-2 dependent.Nature medicine,12(3), 330-334.Colgan, S. P., Serhan, C.

N., Parkos, C. A., Delp-Archer, C., & Madara, J. L. (1993). Lipoxin A4 modulates transmigration of human neutrophils across intestinal epithelial monolayers.Journal of Clinical Investigation,92(1), 75.

技术参数
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