Applications

FA

Synonyms:

NSC263164, EHNA HCl, Adenosine deaminase inhibitor, 9H-Purine-9-ethanol, monohydrochloride

Formulation:

Crystalline solid

Chemical Name:

(2S,3R)-3-(6-aminopurin-9-yl)nonan-2-ol;hydrochloride

Molecular Formula:

C₁₄H₂₃N₅O HCl

Molecular Weight:

313.8

CAS Number

58337-38-5

Purity:

≥98%

Storage Conditions:

Product should be kept at -20°C.

References:

Baker, D. C., Hanvey, J. C., Hawkins, L. D., & Murphy, J. (1981). Identification of the bioactive enantiomer of erthro-3-(adenin-9-YL)-2-nonanol (EHNA), a semi-tight binding inhibitor of adenosine deaminase.Biochemical pharmacology,30(10), 1159-1160.

Woodson, J. C., Minor, T. R., & Soames Job, R. F. (1998). Inhibition of adenosine deaminase by erythro-9-(2-hydroxy-3-nonyl) adenine (EHNA) mimics the effect of inescapable shock on escape learning in rats.Behavioral neuroscience,112(2), 399.

Burton, P., Adams, D., Abraham, A., Allcock, R., Jiang, Z., McCahill, A., ... & Mountford, J. (2010). Erythro-9-(2-hydroxy-3-nonyl) adenine (EHNA) blocks differentiation and maintains the expression of pluripotency markers in human embryonic stem cells.Biochem. J,432, 575-584.