Applications

FA

Synonyms:

alpha 6 Deoxyoxytetracycline, Atridox, Hydramycin, Doxycycline hydrochloride hemiethanolate hemihydrate

Formulation:

Crystalline solid

Chemical Name:

(4S,4aR,5S,5aR,6R,12aR)-4-(dimethylamino)-1,5,10,11,12a-pentahydroxy-6-methyl-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide;ethanol;hydrate;dihydrochloride

Molecular Formula:

2 x [C₂₂H₂₄N₂O₈2HCl] H₂O C₂H₆O

Molecular Weight:

1025.9

CAS Number

24390-14-5

Purity:

≥98%

Storage Conditions:

Product should be kept at -20°C.

References:

Kistner, A., Gossen, M., Zimmermann, F., Jerecic, J., Ullmer, C., Lübbert, H., & Bujard, H. (1996). Doxycycline-mediated quantitative and tissue-specific control of gene expression in transgenic mice.Proceedings of the National Academy of Sciences,93(20), 10933-10938.

Nadelman, R. B., Nowakowski, J., Fish, D., Falco, R. C., Freeman, K., McKenna, D., ... & Wormser, G. P. (2001). Prophylaxis with single-dose doxycycline for the prevention of Lyme disease after an Ixodes scapularis tick bite.New England Journal of Medicine,345(2), 79-84.

Hanemaaijer, R., Visser, H., Koolwijk, P., Sorsa, T., Salo, T., Golub, L. M., & Van Hinsbergh, V. W. M. (1998). Inhibition of MMP synthesis by doxycycline and chemically modified tetracyclines (CMTs) in human endothelial cells.Advances in Dental Research,12(1), 114-118.