名称

规格

货号

价格

G-15

1mg

1160560-1mg

¥1,050

G-15

25mg

1160560-25mg

¥7,070

Applications

FA

Synonyms:

AC1LMJHT, CTK8E6722, ZINC00871833

Formulation:

Crystalline solid

Chemical Name:

(3aR,4R,9bS)-4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline

Molecular Formula:

C₁₉H₁₆BrNO₂

Molecular Weight:

370.2

CAS Number

1161002-05-6

Purity:

≥95%

Storage Conditions:

Product should be kept at -20°C.

References:

Dennis, M. K., Burai, R., Ramesh, C., Petrie, W. K., Alcon, S. N., Nayak, T. K., ... & Prossnitz, E. R. (2009). In vivo effects of a GPR30 antagonist.Nature chemical biology,5(6), 421-427.

Ariazi, E. A., Brailoiu, E., Yerrum, S., Shupp, H. A., Slifker, M. J., Cunliffe, H. E., ... & Jordan, V. C. (2010). The G protein–coupled receptor GPR30 inhibits proliferation of estrogen receptor–positive breast cancer cells.Cancer research,70(3), 1184-1194.

Hammond, R., & Gibbs, R. B. (2011). GPR30 is positioned to mediate estrogen effects on basal forebrain cholinergic neurons and cognitive performance.Brain research,1379, 53-60.