Applications

FA

Synonyms:

Gö6983, Gö 6983, 2-(1-(3-dimethylaminopropyl)-5-methoxyindol-3-yl)-3-(1H-indol-3-yl)maleimide

Formulation:

Crystalline solid

Chemical Name:

3-[1-[3-(dimethylamino)propyl]-5-methoxyindol-3-yl]-4-(1H-indol-3-yl)pyrrole-2,5-dione

Molecular Formula:

C₂₆H₂₆N₄O₃

Molecular Weight:

442.5

CAS Number

133053-19-7

Purity:

≥98%

Storage Conditions:

Product should be kept at -20°C.

References:

Peterman, E. E., & Taormina, P. II, Harvey, M., and Young, LH 2004. Go 6983 exerts cardioprotective effects in myocardial ischemia/reperfusion.J. Cardiovasc. Pharmacol,43, 645-656.

Young, L. H., Balin, B. J., & Weis, M. T. (2005). Gö 6983: a fast acting protein kinase C inhibitor that attenuates myocardial ischemia/reperfusion injury.Cardiovascular drug reviews,23(3), 255-272.

Gschwendt, M., Dieterich, S., Rennecke, J., Kittstein, W., Mueller, H. J., & Johannes, F. J. (1996). Inhibition of protein kinase C μ by various inhibitors. Inhibition from protein kinase c isoenzymes.FEBS letters,392(2), 77-80.