Prostaglandin D2

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Prostaglandin D2

货号:4150768-1

规格:1mg

价格:440

产品类型:小分子化合物

品牌:Biogems

Catalogue Number :4150768

Description

Prostaglandin D2 is the major postagrlandin produced by mast cells and is the primary prostaglandin in the brain. It causes vasodilation, induces inflammation, and its presence in hair follicles may be partially responsible for male pattern baldness. Prostaglandin D2 is released during asthmatic and allergic reactions.

Additional Information

Applications

FA

Synonyms:

11-Dehydroprostaglandin F2alpha, PGD2

Formulation:

Crystalline solid

Chemical Name:

(Z)-7-[(1R,2R,5S)-5-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-3-oxocyclopentyl]hept-5-enoic acid

Molecular Formula:

C20H32O5

Molecular Weight:

352.5

CAS Number

41598-07-6

Purity:

≥98%

Storage Conditions:

Product should be kept at -20°C.

References:

Murray, J. J., Tonnel, A. B., Brash, A. R., Roberts, L. J., Gosset, P., Workman, R., ... & Oates, J. A. (1986). Release of prostaglandin D2 into human airways during acute antigen challenge.New England Journal of Medicine,315(13), 800-804.

Monneret, G., Gravel, S., Diamond, M., Rokach, J., & Powell, W. S. (2001). Prostaglandin D2 is a potent chemoattractant for human eosinophils that acts via a novel DP receptor.Blood,98(6), 1942-1948.

Garza, L. A., Liu, Y., Yang, Z., Alagesan, B., Lawson, J. A., Norberg, S. M., ... & Cotsarelis, G. (2012). Prostaglandin D2 inhibits hair growth and is elevated in bald scalp of men with androgenetic alopecia.Science translational medicine,4(126), 126ra34-126ra34.

技术参数
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