Applications

FA

Synonyms:

Evista, Keoxifene, LY 156758, LY156758

Formulation:

Crystalline solid

Chemical Name:

[6-hydroxy-2-(4-hydroxyphenyl)-1-benzothiophen-3-yl]-[4-(2-piperidin-1-ylethoxy)phenyl]methanone;hydrochloride

Molecular Formula:

C₂₈H₂₇NO₄S HCl

Molecular Weight:

510.2

CAS Number

82640-04-8

Purity:

≥98%

Storage Conditions:

Product should be kept at -20°C.

References:

Delmas, P. D., Bjarnason, N. H., Mitlak, B. H., Ravoux, A. C., Shah, A. S., Huster, W. J., ... & Christiansen, C. (1997). Effects of raloxifene on bone mineral density, serum cholesterol concentrations, and uterine endometrium in postmenopausal women.New England Journal of Medicine,337(23), 1641-1647.

Black, L. J., Sato, M., Rowley, E. R., Magee, D. E., Bekele, A., Williams, D. C., ... & Bensch, W. R. (1994). Raloxifene (LY139481 HCI) prevents bone loss and reduces serum cholesterol without causing uterine hypertrophy in ovariectomized rats.Journal of Clinical Investigation,93(1), 63.

Taranta, A., Brama, M., Teti, A., Scandurra, R., Spera, G., Agnusdei, D., ... & Migliaccio, S. (2002). The selective estrogen receptor modulator raloxifene regulates osteoclast and osteoblast activity in vitro.Bone,30(2), 368-376.