Recombinant Murine Flt3-Ligand
货号：250-31L-10,250-31L-100,250-31L-1000,250-31L-2,250-31L-250,250-31L-50,250-31L-500
规格：10ug,100ug,1mg,2ug,250ug,50ug,500ug
价格：1418,8297,33241,582,14522,4977,21570
产品类型：细胞因子添加物
品牌：PeproTech
| 产品描述：Flt3-Ligand is a growth factor that regulates proliferation of early hematopoietic cells. Flt3-Ligand binds to cells expressing the tyrosine kinase receptor Flt3. Flt3-Ligand, by itself does not stimulate proliferation of early hematopoietic cells, but synergizes with other CSFs and interleukins to induce growth and differentiation. Unlike SCF, Flt3-Ligand has no activity on mast cells. Multiple isoforms of Flt3-Ligand have been identified. The predominant biologically active form is anchored to the cell surface as the extracellular domain of a transmembrane protein (209 a.a.). The membrane-bound isoform can be proteolytically cleaved to generate a biologically active soluble isoform. Recombinant Murine Flt3-Ligand is a soluble 18.6 kDa protein consisting of 163 amino acid residues.来源：E.coli别名：Fms-related tyrosine kinase 3 ligand, FltL氨基酸序列：MTPDCYFSHS PISSNFKVKF RELTDHLLKD YPVTVAVNLQ DEKHCKALWS LFLAQRWIEQ LKTVAGSKMQ TLLEDVNTEI HFVTSCTFQP LPECLRFVQT NISHLLKDTC TQLLALKPCI GKACQNFSRC LEVQCQPDSS TLLPPRSPIA LEATELPEPR PRQ纯度：≥ 98% by SDS-PAGE gel and HPLC analyses.生物活性：Determined by the dose-dependent stimulation of the proliferation of human AML5 cells. The expectedED50for this effect is 5.0 – 8.0 ng/ml.Calculated Molecular Weight:18.6 kDaAccession Number:P49772Gene ID:14256交叉反应：Human,Mouse,Rat |
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