Recombinant Murine IL-1β
货号:211-11B-10,211-11B-100,211-11B-1000,211-11B-2,211-11B-250,211-11B-50,211-11B-500
规格:10ug,100ug,1mg,2ug,250ug,50ug,500ug
价格:1418,8297,33241,582,14522,4977,21570
产品类型:细胞因子添加物
品牌:PeproTech
产品描述:IL-1β is a proinflammatory cytokine produced in a variety of cells, including monocytes, tissue macrophages, keratinocytes, and other epithelial cells. Both IL-1α and IL-1β bind to the same receptor and have similar, if not identical, biological properties. These cytokines have a broad range of activities including the stimulation of thymocyte proliferation by inducing IL-2 release, B cell maturation and proliferation, mitogenic FGF-like activity, and the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1β is a secreted cytokine, IL-1α is predominantly a cell-associated cytokine. Recombinant Murine IL-1β is a 17.5 kDa protein containing 153 amino acid residues.来源:E.coli别名:Catabolin, Lymphocyte-activating factor (LAF), Endogenous Pyrogen (EP), Leukocyte Endogenous Mediator (LEM), Mononuclear Cell Factor (MCF)氨基酸序列:MVPIRQLHYR LRDEQQKSLV LSDPYELKAL HLNGQNINQQ VIFSMSFVQG EPSNDKIPVA LGLKGKNLYL SCVMKDGTPT LQLESVDPKQ YPKKKMEKRF VFNKIEVKSK VEFESAEFPN WYISTSQAEH KPVFLGNNSG QDIIDFTMES VSS纯度:≥ 98% by SDS-PAGE gel and HPLC analyses.生物活性:TheED50as determined by the dose-dependent stimulation of murine D10S cells is ≤ 0.002 ng/ml, corresponding to a specific activity of ≥ 5 x 108units/mg.Calculated Molecular Weight:17.5 kDaAccession Number:P10749Gene ID:16176交叉反应:Human,Human + Hamster,Monkey,Mouse,Mouse + Bacteria,Mouse + Chicken,Mouse + Human,Pig,Rat原产国:USA |
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