Recombinant Human BD-2
货号：300-49-100,300-49-1000,300-49-20,300-49-250,300-49-5,300-49-50,300-49-500
规格：100ug,1mg,20ug,250ug,5ug,50ug,500ug
价格：6410,25699,1425,11216,585,3850,16669
产品类型：细胞因子添加物
品牌：PeproTech
| 产品描述:Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The α-defensins are distinguished from the β-defensins by the pairing of their three disulfide bonds. To date, six human β-defensins have been identified; BD-1, BD-2, BD-3, BD-4, BD-5 and BD-6. β-defensins are expressed on some leukocytes and at epithelial surfaces. In addition to their direct antimicrobial activities, they can act as chemoattractants towards immature dendritic cells and memory T cells. The β-defensin proteins are expressed as the C-terminal portion of precursors, and are released by proteolytic cleavage of a signal sequence and, in some cases, a propeptide sequence. β-defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds. Recombinant Human BD-2 is a 4.3 kDa protein containing 41 amino acid residues.别名:DEFB2, DEFB4A, Beta-Defensin 2, Skin-antimicrobial peptide 1, SAP1氨基酸序列:GIGDPVTCLK SGAICHPVFC PRRYKQIGTC GLPGTKCCKK P来源:E.coli纯度:Greater than 98% by SDS-PAGE gel and HPLC analyses.生物活性:Determined by its ability to chemoattract immature human dendritic cells using a concentration of 10.0-100.0 ng/ml.Calculated Molecular Weight:4.3 kDaAccession Number:O15263Gene ID:1673交叉反应:Bacteria, Rat, Virus, Human原产地:USA仅用于科研，不能用于临床和诊断。 |
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