Recombinant Human BD-1 (47 a.a.)
货号：300-51A-100,300-51A-1000,300-51A-20,300-51A-250,300-51A-5,300-51A-500
规格：100ug,1mg,20ug,250ug,5ug,500ug
价格：6410,25699,1425,11216,585,16669
产品类型：细胞因子添加物
品牌：PeproTech
| 产品描述:Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The α-defensins are distinguished from the β-defensins by the pairing of their three disulfide bonds. To date, six human β-defensins have been identified; BD-1, BD-2, BD-3, BD-4, BD-5 and BD-6. β-defensins are expressed on some leukocytes and at epithelial surfaces. In addition to their direct antimicrobial activities, they can act as chemoattractants towards immature dendritic cells and memory T cells. The β-defensin proteins are expressed as the C-terminal portion of precursors, and are released by proteolytic cleavage of a signal sequence and, in some cases, a propeptide sequence. β-defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds. Recombinant Human BD-1 is a 5.0 kDa protein containing 47 amino acid residues.别名:Beta-Defensin 1, DEFB1, HBD1氨基酸序列:GNFLTGLGHR SDHYNCVSSG GQCLYSACPI FTKIQGTCYR GKAKCCK来源:E.coli纯度:Greater than 98% by SDS-PAGE gel and HPLC analyses.生物活性:Determined by its ability to chemoattract CD34+dendritic cells using a concentration range of 100.0-1000.0 ng/ml.Calculated Molecular Weight:5 kDaAccession Number:P60022Gene ID:1672交叉反应:Human交叉反应:Human原产地:USA仅用于科研，不能用于临床和诊断。 |
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