Human BMP-13/CDMP-2
货号：120-04-10,120-04-100,120-04-50,120-04-250,120-04-1000,120-04-500
规格：10ug,100ug,50ug,250ug,1000ug,500ug
价格：643,3522,1568,6168,14134,9165
产品类型：细胞因子添加物
品牌：PeproTech
| 产品详情产品编号：120-04产品描述：BMP-13 is expressed in hypertrophic chondrocytes during embryonic development of long bones. Continued postnatal expression of BMP-13 in articular cartilage suggests that it plays a regulatory role in the growth and maintenance of articular cartilage. Adenovirus-mediated BMP-13 gene transfer to rabbit bone marrow stem cells have been reported to augment periosteal repair of osteochondral defects. The functional form of BMP-13/CDMP-2 is a disulfide-linked homodimer of two 120 amino acid polypeptide chains. This 27.5 kDa protein is obtained by proteolytic processing of a biologically inactive precursor protein of 97.7 kDa. Recombinant Human BMP-13/CDMP-2 is a 27.0 kDa homodimeric disulfide-linked protein consisting of two 120 amino acid polypeptide chains.Source:E.coliSynonyms:Bone Morphogenetic Protein-13, GDF-6, Cartilage-Derived Morphogenetic Protein-2 (CDMP-2)AA Sequence (monomer):TAFASRHGKR HGKKSRLRCS KKPLHVNFKE LGWDDWIIAP LEYEAYHCEG VCDFPLRSHL EPTNHAIIQT LMNSMDPGST PPSCCVPTKL TPISILYIDA GNNVVYKQYE DMVVESCGCRPurity:≥ 95% by SDS-PAGE gel and HPLC analyses.Biological Activity:TheED50was determined by its ability to induce alkaline phosphatase production by ATDC-5 chondrogenic cells in the range of 2.0-3.0 µg/ml.Calculated Molecular Weight:27 kDaAccession Number:Q6KF10Gene ID:392255crossreactivity:Human,MouseCountry Of Origin:USANot for human use. |
| product.subtitle.recentcitations |
| 第一作者 | Shen, B |
| 标题 | BMP-13 emerges as a potential inhibitor of bone formation.A non-invasive method to generate induced pluripotent stem cells from primate urine |
| 文献引用 | International Journal of Biological Sciences; 5(2) pg192-200PubMed Id |
| PubMed Id | 19240811 |
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