Recombinant Human GDF-2
货号：120-07-2,120-07-10,120-07-100,120-07-1000,120-07-250,120-07-500
规格：2ug,10ug,100ug,1mg,250ug,500ug
价格：643,1568,12235,48997,21395,31787
产品类型：细胞因子添加物
品牌：PeproTech
| 产品详情产品编号：120-07产品描述：GDF-2 belongs to the TGF-β cytokine family, whose members play an important role during prenatal development and postnatal growth, and the remodeling and maintenance of a variety of tissues and organs. GDF-2 is expressed mainly in non-parenchymal cells of the liver, but is also found in other various cells and tissues. GDF-2 can signal through the ALK1 receptor, and has been implicated in a number of physiologic events including the regulation of the hepatic reticuloendothelial system, glucose homeostasis, iron homeostasis, and the inhibition of angiogenesis. Recombinant Human GDF-2 is a 24.1 kDa disulfide-linked homodimeric protein consisting of two 110 amino acid polypeptide chains.Source:CHO cellsSynonyms:Growth/Differentiation Factor-2, BMP-9AA Sequence (monomer):SAGAGSHCQK TSLRVNFEDI GWDSWIIAPKE YEAYECKGGC FFPLADDVTPTK HAIVQTLVHL KFPTKVGKAC CVPTKLSPIS VLYKDDMGVP TLKYHYEGMS VAECGCRPurity:≥ 95% by SDS-PAGE gel and HPLC analyses.Biological Activity:Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. The expectedED50for this effect is 0.5-1.9 ng/ml.Calculated Molecular Weight:24.1 kDaAccession Number:Q9UK05Gene ID:2658crossreactivity:Human,MouseCountry Of Origin:USANot for human use. |
| product.subtitle.recentcitations |
| 第一作者 | Pous, L |
| 标题 | Fibrinogen induces neural stem cell differentiation into astrocytes in the subventricular zone via BMP signaling. |
| 文献引用 | Nature Communications; 11(1) pg630PubMed Id |
| PubMed Id | 32005867 |
| 第一作者 | Dufton, N P |
| 标题 | Dynamic regulation of canonical TGFβ signalling by endothelial transcription factor ERG protects from liver fibrogenesis. |
| 文献引用 | Nature Communications; 8(1) pg895PubMed Id |
| PubMed Id | 29026072 |
| 第一作者 | Redgrave, R E |
| 标题 | Cardiosphere-Derived Cells Require Endoglin for Paracrine-Mediated Angiogenesis |
| 文献引用 | Stem Cell Reports; 8(5) pg1287-1298PubMed Id |
| PubMed Id | 28494939 |
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