Recombinant Human HB-EGF
货号：100-47-10,100-47-100,100-47-1000,100-47-250,100-47-50,100-47-500
规格：10ug,100ug,1mg,250ug,50ug,500ug
价格：582,3187,12787,5581,1418,8292
产品类型：细胞因子添加物
品牌：PeproTech
| 产品描述：HB-EGF is an EGF-related growth factor that signals through the EGF receptor, and stimulates the proliferation of smooth muscle cells (SMC), fibroblasts, epithelial cells, and keratinocytes. HB-EGF is expressed in numerous cell types and tissues, including vascular endothelial cells, and vascular SMC, macrophages, skeletal muscle, keratinocytes, and certain tumor cells. The ability of HB-EGF to specifically bind heparin and heparin sulfate proteoglycans is distinct from other EGF-like molecules, and may be related to the enhanced mitogenic activity, relative to EGF, that HB-EGF exerts on smooth muscle cells. The human HB-EGF gene encodes a 208 amino acid transmembrane protein, which can be proteolytically cleaved to produce soluble HB-EGF. Recombinant Human HB-EGF is a 9.7 kDa protein containing 86 amino acid residues, corresponding to the extracellular EGF-like and heparin-binding domains of the full length HB-EGF protein.来源:E.coli别名:Heparin Binding EGF-like growth factor, HBEGF, Diphtheria toxin receptor (DTR)氨基酸序列:DLQEADLDLL RVTLSSKPQA LATPNKEEHG KRKKKGKGLG KKRDPCLRKY KDFCIHGECK YVKELRAPSC ICHPGYHGER CHGLSL纯度:≥ 95% by SDS-PAGE gel and HPLC analyses.生物活性:Determined by a cell proliferation assay using Balb/c 3T3 cells. The expectedED50is ≤ 1.0 ng/ml, corresponding to a specific activity of ≥ 1 x 106units/mg.Calculated Molecular Weight:9.7 kDaAccession Number:Q99075Gene ID:1839交叉反应:Human,Mouse,Rat原产国:USA |
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